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Indications and physiological effects of fluid bolus therapy in emergency department patients

Indications and physiological effects of fluid bolus therapy in emergency department patients.

Status
Completed
Phases
Unknown
Study type
Observational
Source
ANZCTR
Registry ID
ACTRN12615001150538
Enrollment
500
Registered
2015-10-29
Start date
2014-05-15
Completion date
2015-03-31
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

A prospective study was performed in a tertiary referral centre ED, where the number, types, and volumes of fluid bolus (FB); Indications of fluid bolus.; and their perceived success rates were recorded. The physiological effect of these FBs on blood pressure (MAP, mmHg), heart rate (HR, per minute), respiratory rate (RR, per minute) and temperature (Temp, °C) were recorded before, and 10 minutes, 1 hour, 2 hour and 4 hour after the FB. We hypothesized that, in a tertiary level ED of an Australian teaching hospital, FB therapy will have varied indications and have limited physiological efficacy.

Interventions

Indications and physiological efficacy of fluid bolus therapy in any patients presenting to the Emergency Department. Decision regarding the administration of the fluid bolus therapy will be at the discretion of the treating physician. The duration of follow up will be up to 4 hours after administration of fluid bolus. The data will be collected prospectively.

Sponsors

Department of ICCU, Flinders Medical Centre
Lead SponsorHospital

Eligibility

Sex/Gender
All
Age
16 Years to No maximum
Healthy volunteers
No

Inclusion criteria

Any patients requiring a fluid bolus in the emergency department

Exclusion criteria

We excluded patients if their age was less than 16 years, were transferred from another hospital, or they already had more than 1000 ml of fluids administered in the ambulance while being transferred to the hospital

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026