None listed
Conditions
Brief summary
The purpose of this study is to understand how different foods can affect blood glucose responses when a young person sits for a long period of time and when that sitting is interrupted with light exercise breaks. We hypothesise that the glucose responses will be minimised when healthier foods are eaten and when the sitting is interrupted by light exercise breaks.
Interventions
Adolescents, aged 14-17 years from Melbourne suburbs, will participate in a four-treatment, acute crossover trial in a laboratory setting. The four trial conditions involve: 1) uninterrupted sitting for 6h and consumption of two ‘healthy’ meals (at 0h and 3h; consistent for each condition); 2) sitting for 6 hours with 2-min interruptions every 18 minutes and consumption of two ‘healthy’ meals; 3) uninterrupted sitting for 6h and consumption of two ‘unhealthy’ meals; and 4) sitting for 6 hours wi
Adolescents, aged 14-17 years from Melbourne suburbs, will participate in a four-treatment, acute crossover trial in a laboratory setting. The four trial conditions involve: 1) uninterrupted sitting for 6h and consumption of two ‘healthy’ meals (at 0h and 3h; consistent for each condition); 2) sitting for 6 hours with 2-min interruptions every 18 minutes and consumption of two ‘healthy’ meals; 3) uninterrupted sitting for 6h and consumption of two ‘unhealthy’ meals; and 4) sitting for 6 hours with 2-min interruptions sitting every 18 minutes and consumption of two ‘unhealthy’ meals. Both the healthy and unhealthy meal contains the same macronutrient content (e.g. 55% carbohydrates, 30% from fat and 15% from protein). However, the ‘healthy’ meal is 25% of the daily recommended energy intake (2,802kj) and follows the dietary guidelines for healthy eating (e.g. contains whole grains, lean meat, is low in sodium, high in fibre etc). Whereas the ‘unhealthy’ meal contains 1.5 times more kilojoules (4,203kj) and does not follow the guidelines (e.g. low in fibre, high in sodium, refined carbohydrates etc). Participants will be asked to consume the meals within 20 minutes, and any food or drink left over will be recorded and accounted for in the analyses. Each condition will be performed on separate days with a rest day/washout period in between conditions. Prior to beginning, participants will be fitted with a Continuous Glucose Monitoring (CGM) system to monitor interstitial blood glucose and wear an accelerometer and inclinometer to objectively measure their sedentary and sitting time, respectively, during each condition. The interruptions during condition 2 and 4 will involve two minutes of simple exercises such as body squats, calf raises, gluteal contractions, and step-ups. During all four conditions, all participants will be supervised by research staff to ensure compliance to the protocol.
Sponsors
Deakin University
Study design
Allocation
Non-randomised trial
Intervention model
Crossover
Primary purpose
Prevention
Masking
Open (masking not used)
Eligibility
Sex/Gender
All
Age
14 Years to 17 Years
Healthy volunteers
Yes
Inclusion criteria
Adolescents aged between 14- 17 years Living in Melbourne, Australia
Exclusion criteria
1) On any lipid or glucose lowering medications that may affect glucose and lipid metabolism (e.g. anti-depressants, etc); 2) Chronic (>twice/week) use of prescribed medication that can effect glucose metabolism (e.g. anti-depressants and antipsychotic); 3) Chronic (>twice/week) use of nonsteroidal anti-inflammatory drugs (e.g. aspirin, ibuprofen and naproxen): 4) Use of asthma medicines; 5) Daily antioxidant supplementation; 6) Diagnosed type 2 diabetes, glucose intolerance, cardiovascular disease, hypertension, and/or an abnormal lipid profile; 7) Diet allergies to gluten, lactose or fructose, nuts, and if vegetarian or vegan; and 8) BMI >35kg/m2
Outcome results
None listed