None listed
Conditions
Brief summary
The symptoms of Allergic rhinitis, such as nasal congestion and itching, are a burden for an estimated 3.2 million Australians and its prevalence is increasing. There is growing evidence to suggest that probiotic supplementation elicits beneficial health effects on the host through modulation of the immune system and thereby can improve symptoms associated with Allergic rhinitis. The aim of this research is to examine the effect of probiotic supplementation on symptoms and quality of life in individuals suffering from Allergic rhinitis
Interventions
Daily probiotic Supplementation for 8 weeks. The supplement is in the form of a powder (2g twice daily) to be mixed with water and consumed orally.
The supplement composition is as follows: Maize starch, Maltodextrins, Bacterial strains (Bifidobacterium bifidum W23, Lactobacillus acidophilus W55, Lactobacillus casei W56, Lactobacillus salivarius W57 and Lactococcus lactis W58 - >1x10^9 cfu/g) Vitamin B2 and Biotin.
Compliance will be encouraged with a daily checklist and monitored by supplem
Daily probiotic Supplementation for 8 weeks. The supplement is in the form of a powder (2g twice daily) to be mixed with water and consumed orally. The supplement composition is as follows: Maize starch, Maltodextrins, Bacterial strains (Bifidobacterium bifidum W23, Lactobacillus acidophilus W55, Lactobacillus casei W56, Lactobacillus salivarius W57 and Lactococcus lactis W58 - >1x10^9 cfu/g) Vitamin B2 and Biotin. Compliance will be encouraged with a daily checklist and monitored by supplementation return at the end of the intervention period.
Sponsors
Griffith University
Study design
Allocation
Non-randomised trial
Intervention model
Single group
Primary purpose
Treatment
Masking
Open (masking not used)
Eligibility
Sex/Gender
All
Age
17 Years to 60 Years
Healthy volunteers
No
Inclusion criteria
For inclusion in the study participants are required to be aged between 17-60, have a history of moderate to severe persistent Allergic rhinitis, test positive to both a skin prick test and a radio-allergosorbent test to Bermuda (couch) grass.
Exclusion criteria
Participants will be excluded from the study if they: Suffer from non-allergic rhinitis; Do not test positive for on the skin prick test and radio-allergosorbent test to Bermuda grass; Have undergone treatment with systemic corticosteroids in the previous 6 months; Have a history of respiratory or immune diseases; Use of anti-inflammatory or immune modulating medications; Consumption of probiotics or prebiotic supplements in the previous 12 weeks; Use of Antibiotics within the last 30 days; Are pregnant or intending to become pregnant during the trial period;
Outcome results
None listed