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Timely intervention: Efficacy of a depression symptom monitoring smartphone app to deliver psychological intervention at time of greatest need

In patients with depression, does a guided app-based intervention, compared to self-guided app, reduce depressive symptom severity?

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12615001093572
Enrollment
600
Registered
2015-10-19
Start date
2015-10-20
Completion date
2016-10-28
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

The purpose of this project is to conduct a randomised controlled trial (RCT) to compare self-guided use of an online intervention resource against BlueWatch-enhanced use of the same content. BlueWatch monitors depressive symptoms throughout the duration of intervention, and uses this information to obtain a risk profile for each participant, which can be used to predict periods of greater risk of depressed mood. In instances where greater risk is identified, participants are recommended to use the intervention resources immediately. It is hypothesized that this guided use will lead to stronger and quicker improvement in depressive symptoms, and due to the tailored nature of the intervention, will have lower dropout rates than self-guided use of the same intervention resources.

Interventions

Arm 1: self-guided use of a smartphone app-based intervention for depression. This group is given access to the intervention materials (via app), with the instructions to complete each of the 12 x 30 minute modules in sequence. It is emphasized that the modules are designed to be paced at one per week. The treatment material consists of six modules based on 3rd Wave Cognitive and Behavioural approaches to treat negative moods and build personal resilience: (1) Acceptance and Commitment Therapy (

Arm 1: self-guided use of a smartphone app-based intervention for depression. This group is given access to the intervention materials (via app), with the instructions to complete each of the 12 x 30 minute modules in sequence. It is emphasized that the modules are designed to be paced at one per week. The treatment material consists of six modules based on 3rd Wave Cognitive and Behavioural approaches to treat negative moods and build personal resilience: (1) Acceptance and Commitment Therapy (ACT) to identify personal values (2) Cognitive Behaviour Therapy (CBT) to uncover and dispute unhelpful thinking styles and their underlying assumptions, (3) Mindfulness Based Cognitive Behavioural Therapy (MCBT) to learn to accept negative thoughts without judgment, (4) resilience building to learn to maintain healthy levels of self-esteem, optimism, and to savour acts of kindness and gratitude, (5) Behavioural Activation to increase exposure to positive situations that provide meaning and/or pleasure and, (6) Troubleshooting/Relapse prevention. Arm 2: app-enhanced use of a smartphone app-based intervention for depression. This group is also given access to the intervention materials, with the same instructions for self-guided use (i.e., complete one module per week for 12 weeks). However, they are also informed that, based on their scores on the brief app surveys (given up to four times per day, measuring current mood state), they will be invited to undertake brief, additional content (top-up activities) at times of greatest need (i.e., when their depressive mood state scores are elevated they may be recommended to complete a brief relaxation task). These top-up activities are similar to the activities they receive in the online training, but are prompted by scores deemed at risk by the app surveys. Please note, these top-up activities are additional to, rather than substitutes for, the 12 weeks of module content, and participants are encouraged to continue to progress through the 12 modules at the same pace as recommended for Arm 1 participants (regardless of how many times they may engage in top-up activities). Both groups will have access to the intervention content for 12 weeks. Adherence and usage is monitored by the app for both groups.

Sponsors

Dr Matthew Fuller-Tyszkiewicz
Lead SponsorIndividual

Study design

Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Open (masking not used)

Eligibility

Sex/Gender
All
Age
18 Years to 25 Years
Healthy volunteers
No

Inclusion criteria

(1) Aged 18-25 years (2) Scores of greater than or equal to 10 on the PHQ9, which indicates at least moderate depression (3) Access to a smartphone for the duration of testing to access and use our app

Exclusion criteria

(1) Not fluent in English (2) Currently seeking psychological treatment for depressive symptoms (3) Initiation of antidepressant medication within 1 month of starting this study (4) Severe psychiatric condition (such as psychosis, suicidality, or bipolar disorder) that would necessitate intensive therapy (5) Doesn't have access to a smartphone with internet access for duration of study

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026