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Effect of patient-specific multi-scale computer modelling to aid decision making versus standard decision making by surgeon on coronary blood flows in patients undergoing coronary artery bypass graft surgery

Effect of patient-specific multi-scale computer modelling to aid decision making versus standard decision making by surgeon on coronary blood flows in patients undergoing coronary artery bypass graft surgery

Status
Not yet recruiting
Phases
Unknown
Study type
Observational
Source
ANZCTR
Registry ID
ACTRN12615000954527
Acronym
COMCAB study
Enrollment
10
Registered
2015-09-11
Start date
2015-11-02
Completion date
Unknown
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

The creation of a computer model to aid in a cardiac surgeons' decision-making regarding their coronary artery bypass grafting strategy. Specifically to determine which vessels are graftable, whether they should be sequential grafts, the number of grafts to perform and to further delineate the issue of competitive flows.

Interventions

Computer model will be created on the basis of each patients coronary angiogram and cardiac CT scan. Patients will have intraoperative measurements done by ultrasound of the flows down their grafts and coronary arteries as well as an additional post-operative cardiac CT scan. The intraoperative measurements will be take less than 5 minutes and will not increase cardiopulmonary bypass time. The surgeon performing the operation will show their own discretion as to what grafting procedure they will

Computer model will be created on the basis of each patients coronary angiogram and cardiac CT scan. Patients will have intraoperative measurements done by ultrasound of the flows down their grafts and coronary arteries as well as an additional post-operative cardiac CT scan. The intraoperative measurements will be take less than 5 minutes and will not increase cardiopulmonary bypass time. The surgeon performing the operation will show their own discretion as to what grafting procedure they will perform. Other surgeons will be surveyed afterwards and given the information of the computer model and will be free to interpret the model at their discretion to decide what grafting strategy they would have used. This will include which vessels they would have chosen to graft, whether or not they would use sequential grafts and which conduits they would use.

Sponsors

Auckland City Hospital
Lead SponsorHospital

Eligibility

Sex/Gender
All
Age
30 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

Patients *undergoing a planned isolated coronary artery bypass grafting operation *competence to provide informed consent *normal left ventricular ejection fraction Surgeons *an expert in coronary surgery having been in practice for at least 10 years and/or performed more than 1000 coronary artery cases

Exclusion criteria

Patients *emergency or salvage coronary artery bypass operations *significant renal impairment Surgeons *not willing to provide informed consent to participate in the study

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026