None listed
Conditions
Brief summary
This study comprises part of a PhD project. It aims to identify what are the primary mechanisms responsible for muscle growth following light-load blood-flow restriction training in the legs, and how it can also affect muscles in other limbs. This will be compared with an equal-intensity training group without blood-flow restriction, a heavy-load resistance training group, and an untrained control group. This will be investigated using a seven week strength training study.
Interventions
The intervention(s) are seven-week training programs where participants train at the lab three days per week for 45 min training sessions. Interventions will occur on an individual basis supervised by a trained exercise physiologist. There are three different interventions, of which participants will perform one only (random allocation).
Intervention 1: Blood-flow restriction (BFR)
Exercises performed are bicep curls (3 sets; 10 repetitions; 50% 1 RM) performed by the dominant arm followed by f
The intervention(s) are seven-week training programs where participants train at the lab three days per week for 45 min training sessions. Interventions will occur on an individual basis supervised by a trained exercise physiologist. There are three different interventions, of which participants will perform one only (random allocation). Intervention 1: Blood-flow restriction (BFR) Exercises performed are bicep curls (3 sets; 10 repetitions; 50% 1 RM) performed by the dominant arm followed by four sets of bilateral knee flexion and leg extension exercises (1 set x 30 reps, 3 sets x 15 reps; 30% 1 RM). The rest period between bicep curl sets is 3 min. The rest period between leg extension and knee flexion sets is 30 sec. The leg exercises are performed with pressurised cuffs applied to the most proximal portion of the upper legs to restrict blood-flow to the working muscles. These cuffs are inflated to a pressure equal to 60% of the pressure required to completely occlude blood-flow through the legs. Participants are supervised/monitored throughout all training sessions to ensure safety and adherence to the protocol. Intervention 2: High-intensity (HI) Exercises: Dominant arm bicep curls (3 sets; 10 repetitions; 50% 1 RM), Knee flexion (4 sets; 8 repetitions; 80% 1 RM) and leg extension (4 sets; 8 repetitions; 80% 1 RM). No blood-flow restriction applied. The rest period between bicep curl sets is 3 min. The rest period between leg extension and knee flexion sets is 2 min.
Sponsors
Stuart Warmington
Study design
Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Open (masking not used)
Eligibility
Sex/Gender
Male
Age
18 Years to 30 Years
Healthy volunteers
Yes
Inclusion criteria
Male 18-30 years of age Not regularly strength trained within six months of recruitment.
Exclusion criteria
Those unable to satisfy the vigorous exercise requirements of the Adult Pre-exercise Screening System tool. People with blood-clotting disorders People that have performed regular resistance training in the last six months. Female People with diagnosed cardiovascular disease, uncontrolled hypertension, high resting blood pressure or heart rate. People who cannot easily comfortably perform the exercise due to musculoskeletal injuries. People in existing dependent or unequal relationships with project staff.
Outcome results
None listed