Performance and complications of hysteroscopic adhesiolysis of in women complaining of reproductive failure due to intrauterine adhesions.

Efficacy and safety of hysteroscopic adhesiolysis in women with intra-uterine adhesions who are trying to become pregnant

Status

Completed

Phases

Unknown

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12615000899549

Enrollment

Registered

2015-08-27

Start date

2009-02-01

Completion date

2013-10-31

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

This study aimed to assess the efficacy and safety of hysteroscopic adhesiolysis in patients with bad obstetric outcome due to intrauterine adhesions.

Interventions

Hysteroscopy is the method of choice to diagnose, treat and follow up patients with intrauterine adhesions. steps of hysteroscopic adhesiolysis: the procedure was carried out with senior gynaecological endoscopist. The cervix was dilated to Hegar dilator 6. A forward oblique 30 degree, hysteroscopy was inserted inside the uterine cavity that was distended with 0.9% normal saline at inflow pressure of 60–90 mmHg, using a special machine, hysterometer, which was used to adjust the pressure of the flow, the amount of the distension media fluid used and the deficit after the operation. The operative hysteroscopy used was 5.5 mm outer sheath diameter that permits the use of 3-5 French diameter semi-rigid scissors to lyse the adhesion at the junction of the adhesion with the endometrium and excise the tissue. Duration of hysteroscopy procedure was ranged between 10 – 52minutes with average time was 29 minutes.

Study design

Allocation

Non-randomised trial

Intervention model

Single group

Primary purpose

Treatment

Masking

Open (masking not used)

Eligibility

Sex/Gender

All

Age

18 Years to 37 Years

Healthy volunteers

Inclusion criteria

Patients trying to get pregnant with intra-uterine adhesions that affect their reproductive carrier, with no contraindication for either pregnancy or surgery

Exclusion criteria

Age more than 37 years old, other causes of amenorrhea or reproductive failure as ovulatory disorder, tubal block, pelvic adhesions diagnosed by laparoscopy, PID or male factors of infertility.

Outcome results