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Psychological Stress in intensive care survivors

Psychological stress in post intensive care survivors and their family members

Status
Completed
Phases
Unknown
Study type
Observational
Source
ANZCTR
Registry ID
ACTRN12615000880549
Acronym
PRICE
Enrollment
327
Registered
2015-08-24
Start date
2015-07-03
Completion date
2017-05-01
Last updated
2025-09-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

A significant proportion of patients who have survived admission to an Intensive Care Unit (ICU) experience long-term psychological consequences that include anxiety, depression and post-traumatic stress disorder (PTSD). A high proportion of family members of ICU patients also present with varying psychological symptoms of anxiety, depression and PTSD. Currently there are no routine follow ups of psychological well-being of patients discharged from intensive care units in Australia. There are little data from Australia about the incidence of psychological stress in the local population of ICU survivors and family members. Understanding of the incidence of the psychological stress in ICU survivors and their family members could potentially lead to routine assessment of the problem and measures to reduce the incidence. The primary aim of this multicentre study is to determine and compare the prevalence of affective symptoms in intubated and non-intubated ICU survivors and their family members by screening them for PTSD, anxiety, depression and Health Related Quality of Life (HRQoL) over a 12-month follow up period. The secondary aims of this study are to identify the risk factors for adverse psychological outcomes in ICU survivors.

Interventions

3 and 12 month follow up of intensive care survivors and their family members for prevalence of Post Traumatic Stress Disorder (PTSD); depression; anxiety and health related quality of life.

Sponsors

Sumeet Rai
Lead SponsorIndividual

Eligibility

Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

A) Intubated ICU survivor: * Age 18 years and older * Able to consent * Intubated and mechanically ventilated for more than 24 hours AND ICU stay for more than 72 hours B) Non intubated ICU survivor: * Age 18 years and older * Able to consent * Not been intubated during current ICU stay * Received inotropic/vasopressor support and/or non invasive ventilation during ICU stay * ICU stay for less than 72 hours Family Members * Family member (spouse/partner/next of kin/lives with patient normally) of patients with above criteria * Age 18 years and older

Exclusion criteria

Common criteria * Background psychiatric history (schizo affective disorders, chronic PTSD) * Non English Speaking Background (screening tests are validated in English) * Imminent death/palliative care patient (exclusion as a result of unlikely follow up at 2 months) ICU patient survivors (additional criteria) * Suspected acute primary brain lesion that may result in global impairment of conscious level or cognition, such as traumatic brain injury, intracranial haemorrhage, stroke, or hypoxic brain injury. * Unable to give informed consent prior to hospital discharge.

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 22, 2026