Curcumin for the treatment of attention deficit hyperactivity disorder (ADHD) - a randomised, double-blind, placebo-controlled study

Status

Completed

Phases

Unknown

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12615000790549

Enrollment

Registered

2015-07-30

Start date

2015-08-12

Completion date

2016-01-29

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

This is a double-blind, placebo controlled study assessing the therapuetic effects of curcumin in 60 youth suffering from ADHD or significant attentional problem. Participants will be randomly allocated into either a curcumin (BCM-95 'Registered Trademark' - 250-500mg twice daily) or placebo group and changes in ADHD symptoms and general behaviour will be measured over a 12-week period.

Interventions

Curcumin capsules containing 250-500mg of a proprietary blend of curcumin (BCM-95 'Registered Trademark') will be consumed twice daily for 12 weeks by children diagnosed with ADHD or with significant attentional problems. Adherence to capsule intake will be monitored through capsule return and count.

Study design

Allocation

Randomised controlled trial

Intervention model

Parallel

Primary purpose

Treatment

Masking

Blinded (masking used) (Subject, Caregiver)

Eligibility

Sex/Gender

All

Age

6 Years to 14 Years

Healthy volunteers

Inclusion criteria

1. Child is a healthy male or female aged between 6 and 14 years 2. Child has been diagnosed with ADHD or significant attentional problem, as assessed by investigators 3. Child is willing and able to swallow capsules. 4. Preferable, but not essential. Child’s teacher is willing to complete questionnaires (at the beginning and end of the study)

Exclusion criteria

1. Current or 12-month history in your child of any psychiatric disorder other than ADHD, oppositional defiant disorder or similar behavioural disorder (moderate-to-high severity). 2. Child is currently taking any pharmaceutical medication (including ADHD medication), apart from the occasional use (no more than fortnightly) of pain-relievers (e.g., ibuprofen, panadeine). 3. Child is currently taking turmeric/ curcumin supplements and/or other specific herbal products 4. Child has current or history of clinically significant chronic medical condition including cardiovascular disease, organic brain disorder, seizure, diabetes 5. Child currently abuses or is dependent on drugs 6. Child has any learning problem significantly affecting his/her educational achievement

Outcome results