None listed
Conditions
Brief summary
This study will test whether a single dose of oxytocin influences body perception. Body perception will be examined using a multi-sensory illusion, in which individuals experience a sense of ownership for a prosthetic limb, involving integration of visual, tactile and proprioceptive sensory information. Perceptual and kinematic effects of this illusion will be assessed. Oxytocin will be delivered via nasal spray, and compared to a placebo spray in a repeated measures design. Participants will be healthy adult males. The effects of oxytocin on body perception will be examined with respect to autism spectrum traits (in the sample of healthy volunteers). It is hypothesised that oxytocin will facilitate the effects of the illusion.
Interventions
This study will employ a double-blind placebo controlled within-subjects design. Each participant will complete two treatment conditions, separated by a minimum of one week. The treatment conditions will involve a single dose of either placebo or oxytocin (24 IU of Syntocinon spray), delivered by intranasal spray. Participants will receive each treatment in the laboratory, supervised by an experimenter.
Sponsors
Professor Jakob Hohwy
Study design
Allocation
Non-randomised trial
Intervention model
Crossover
Primary purpose
Treatment
Masking
Blinded (masking used) (Subject, Caregiver, Outcomes Assessor)
Eligibility
Sex/Gender
Male
Age
18 Years to 55 Years
Healthy volunteers
Yes
Inclusion criteria
Healthy male adults.
Exclusion criteria
Individuals who meet the following criteria will be excluded from participating in this study: - Current depression or psychosis. - A personal or family history of a diagnosis of any neurological/psychiatric disorders - Currently on medication known to have an impact on mood or cognitive performance (e.g., antidepressants, anxiolytics, etc) - A history of substance abuse or head injury - Current smokers - Have an artificial cardiac pacemaker.
Outcome results
None listed