Effect of timing of kiwifruit ingestion relative to consumption of a breakfast cereal on the glycaemic response to the breakfast cereal

Kiwifruit will be consumed by healthy subjects at different times before and after consuming a breakfast cereal in order to determine at which time point relative to the cereal ingestion, the kiwifruit is most effective at reducing the blood glucose response to the cereal

Status

Completed

Phases

Unknown

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12615000744550

Enrollment

Registered

2015-07-20

Start date

2015-06-29

Completion date

2015-07-12

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

The aim of the study is to determine how much the proximity of kiwifruit ingestion to ingestion of a glycaemic breakfast cereal affects the ability of the kiwifruit to reduce the blood glucose raising effect of the breakfast cereal. Kiwifruit (200 g edible portion) will be consumed 11 h, 90 min, and 30 min before, at the same time as, and 30 min after consuming the breakfast cereal. Blood glucose responses will be measured to allow calculation of the blood glucose response as the area under the blood glucose response curve.

Interventions

Subjects will be asked to consume a glycaemic (GI > 70) breakfast cereal (60 g) after an overnight fast. They will also be asked to consume the edible portion of two gold kiwifruit (200 g) either at 11 h, or 90 min or 30 min before, or at the same time as, or 30 min after consuming the breakfast cereal (ie at 10 pm, or 7.30 am or 8.30 am or 9.00 am or 9.30 am, with the cereal consumed at 9.00 am. Each time interval will be in a different session, with at least two days between sessions. Baseline blood glucose measurements will be taken immediately before the first food intake in the morning and at intervals afterward to allow blood glucose response profiles to be constructed for each occasion. All consumed food is supplied and experimenter follows postprandial responses.

Study design

Allocation

Randomised controlled trial

Intervention model

Crossover

Primary purpose

Prevention

Masking

Open (masking not used)

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Healthy volunteers

Yes

Inclusion criteria

Willingness to meet the requirements of the study, that is, to follow instructions to fast overnight and to not consume food other than the trial meal during the blood glucose measurement periods. Not intolerant of kiwifruit or gluten.

Exclusion criteria

Glucose intolerance

Outcome results