None listed
Conditions
Brief summary
This study aims to describe the effect of limb compression on lymphoedema in terms of fluid distribution and soft tissue structure changes using MRI. Who is it for? You may be eligible to join this study if you are aged 18 years or above and have a clinically detectable unilateral secondary upper limb lymphoedema arising from treatment of breast cancer. This diagnosis must be made using accepted diagnostic thresholds for bioimpedance spectroscopy (BIS) or volume measurements. You must also currently use a compression garment for management of your lymphoedema. All participants enrolled in this study will have at least one MRI scan while wearing the upper limb compression garment. Depending on participant availability, a second MRI scan on a separate visit may also be performed where participants do not wear the compression garment for that day. It is hoped that this study will contribute to a better understanding of how different levels of compression can be used in control of the lymphoedema.
Interventions
Women will undergo two MRI scans on their arm - one while wearing their own compression garment and the other without. Compression garments will not be provided as a part of the study. The current recommendation is for compression to be used continuously (International Lymphoedema Framework, 2012). For persons with upper limb LE, the recommendation is to use at least 30 to 40 mmHg (Class II garment).
Sponsors
University of Sydney
Study design
Allocation
Non-randomised trial
Intervention model
Single group
Primary purpose
Treatment
Masking
Open (masking not used)
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Healthy volunteers
No
Inclusion criteria
- clinically detectable unilateral secondary upper limb lymphoedema arising from treatment of breast cancer using accepted diagnostic thresholds for bioimpedance spectroscopy (BIS) or volume measurements; - if they can attend Spectrum Imaging, Randwick on one or two occasions, and - if they understand English and consent to participate, and - if they currently use compression garments to manage their lymphedematous arm
Exclusion criteria
if they do not have clinically detectable lymphoedema on the day of testing, if they have a pacemaker or other metal implant, if they suffer from claustrophobia; if they are unable to lie on their stomach with their arms above their head or if they have primary or bilateral upper limb lymphoedema.
Outcome results
None listed