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Analgesic efficacy of paravertebral dexmedetomidine in children undergoing renal surgery

In children undergoing renal surgery, does paravertebral dexmedetomidine added to bupivacaine, compared to paravertebral bupivacaine only, reduce postoperative opioid consumption?

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12615000708550
Enrollment
80
Registered
2015-07-09
Start date
2015-09-01
Completion date
Unknown
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Evaluation of postoperative analgesic efficacy of paravertebral dexmedetomidine when added to bupivacaine in pediatric patients undergoing renal surgery

Interventions

After induction of anesthesia and before skin incision, for group PD, with the patient in the lateral decubitus position and the operated side facing upwards. Needle insertion will be made at an easily palpated single low thoracic level (Th10–12) lateral to the spinal process. The distance from the midline will be (approximating the distance between the patient’s two adjacent spinous processes). A 22 G Tuohy needle will be inserted perpendicularly to the skin in all planes until contact with t

After induction of anesthesia and before skin incision, for group PD, with the patient in the lateral decubitus position and the operated side facing upwards. Needle insertion will be made at an easily palpated single low thoracic level (Th10–12) lateral to the spinal process. The distance from the midline will be (approximating the distance between the patient’s two adjacent spinous processes). A 22 G Tuohy needle will be inserted perpendicularly to the skin in all planes until contact with the transverse process. The needle will be then advanced under or over the transverse process and after piercing the costo-transverse ligament, the paravertebral space was identified by loss of resistance to air. After careful aspiration, a single bolus dose of 0.5 ml / kg of Bupivacaine 0.25% and 1.5 mic /kg dexmedetomidine will be injected.

Sponsors

diab fuad hetta
Lead SponsorIndividual

Study design

Allocation
Randomised controlled trial
Primary purpose
Treatment

Eligibility

Sex/Gender
All
Age
3 Years to 12 Years
Healthy volunteers
No

Inclusion criteria

1-Renal surgery 2-patients with physical status American Society of Anaesthesiologist (ASA) I , II and III

Exclusion criteria

1-contraindication to PVB (infection at site of injection, coagulopathy, vertebral anomalies) 2- allergy to drugs used in the study

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026