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Preventing tooth decay in children in a remote community in Australia.

Effectiveness, cost-effectiveness and cost-benefit of a single annual professional intervention for the prevention of childhood dental caries in a remote rural Indigenous community.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12615000693527
Enrollment
434
Registered
2015-07-03
Start date
2015-08-01
Completion date
2015-11-30
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Background: The aim of the study is to reduce the high prevalence of tooth decay in children in a remote, rural Indigenous community in Australia, by application of a single annual dental preventive intervention. The study seeks to (1) assess the effectiveness of an annual oral health preventive intervention in slowing the incidence of dental caries in children in this community, (2) identify the mediating role of known risk factors for dental caries and (3) assess the cost-effectiveness and cost-benefit of the intervention. Methods/Design: The intervention is novel in that most dental preventive interventions require regular re-application, which is not possible in resource constrained communities. While tooth decay is preventable, self-care and healthy habits are lacking in these communities, placing more emphasis on health services to deliver an effective dental preventive intervention. Importantly, the study will assess cost-benefit and cost-effectiveness for broader implementation across similar communities in Australia and internationally. Discussion: There is an urgent need to reduce the burden of dental decay in these communities, by implementing effective, cost-effective, feasible and sustainable dental prevention programs. Expected outcomes of this study include improved oral and general health of children within the community; an understanding of the costs associated with the intervention provided, and its comparison with the costs of allowing new lesions to develop, with associated treatment costs. Findings should be generalisable to similar communities around the world.

Interventions

The dental prevention model will essentially reduce the microbial load with the topical disinfectant, povidone iodine; inhibit biofilm adherence to susceptible sites by application of fissure sealants and reduce the susceptibility of the tooth to demineralisation by acids generated in the microbial biofilm by the application of a fluoride varnish. Topical Treatment by PVP-Iodine in conjunction with Fluoride Varnish is simple. The iodine comes in a single application swab. The total treatment t

The dental prevention model will essentially reduce the microbial load with the topical disinfectant, povidone iodine; inhibit biofilm adherence to susceptible sites by application of fissure sealants and reduce the susceptibility of the tooth to demineralisation by acids generated in the microbial biofilm by the application of a fluoride varnish. Topical Treatment by PVP-Iodine in conjunction with Fluoride Varnish is simple. The iodine comes in a single application swab. The total treatment time is 3 to 4 minutes and costs less than 20 cents. Clinically the teeth are brushed to remove debris and disrupt the biofilm; then dried with gauze, and painted with 0.2 ml PVP-Iodine. After the iodine application, the teeth are dried again and coated with fluoride varnish at the same visit. Product Name: Povidone Iodine Pads and Swabsticks. Fluoride varnishes are a liquid resin or synthetic base that contain a high concentration of fluoride and set quickly on contact with teeth, even in the presence of saliva. The fluoride varnish takes 3-5 minutes to apply. Fluoride ions in the material are released when the pH drops in response to acid production in the biofilm on the tooth surface and these become available to promote remineralisation of damaged tooth enamel in early carious lesions (white spots). The fluorhydroxyapatite formed over time during the remineralisation process in an initial caries lesion is more resistant to future demineralisation. Product Name: Colgate Durphat -  Varnish Single Dose 5% Sodium Fluoride (22,600 ppm). Dental decay most often occurs on the occlusal pits and fissures of permanent molar teeth. A pit and fissure sealant is defined as a material [both glass-ionomer and resin-based materials are widely used] that is introduced into the occlusal pits and fissures of caries susceptible teeth. Fissues sealant applications take about 15-30 minutes to complete. Product Name: Conseal-Clear, Conseal-Light Grey, Conseal F (White). These interventions will be administered by a dentist or oral/dental health therapist, at baseline, years 1 and 2 of the study. All participants will receive the identical preventive intervention.

Sponsors

Griffith University
Lead SponsorUniversity

Study design

Allocation
Non-randomised trial
Intervention model
Single group
Primary purpose
Prevention
Masking
Open (masking not used)

Eligibility

Sex/Gender
All
Age
4 Years to 17 Years
Healthy volunteers
No

Inclusion criteria

All children (approximately 600-650) attending the two primary and one secondary school campuses will be invited to participate in the intervention study.

Exclusion criteria

None

Outcome results

None listed

Source: ANZCTR · Data processed: Mar 15, 2026