Prospective study investigating relation between preoperative quality of sleep with anesthetic requirements

comparing anesthetic drugs requirements in preoperative poor quality sleepers versus good quality sleepers undergoing elective surgery

Status

Completed

Phases

Unknown

Study type

Observational

Source

ANZCTR

Registry ID

ACTRN12615000675527

Enrollment

Registered

2015-06-29

Start date

2012-06-01

Completion date

2013-01-01

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Sleep disturbances are common among surgical patients in the preoperative period due to anxiety. Since general anesthesia and physiological sleep share many similarities, the aim of this study is to examine the relation between preoperative quality of sleep and intraoperative anesthetic requirements and postoperative analgesic requirements.

Interventions

evaluation of preoperative sleep quality using sleep electroencephalogram EEG for 8 hours on the night before surgery, recording induction dose of propofol needed to achieve bispectral index BIS value 40-60, recording intraoperative isoflurane requirements needed to achieve BIS 40-60 every 3 minutes

Eligibility

Sex/Gender

Male

Age

20 Years to 40 Years

Healthy volunteers

Inclusion criteria

ASA physical status 1 and 2, Body mass index BMI 25-30, Normal sleep wake pattern, Patient with Epworth sleepiness scale scores less than 5, patients scheduled for elective open cholecystectomy, open upper abdominal hernia mesh repair, male patients only due to cultural obstacles to sleep EEG measurements.

Exclusion criteria

History of sleep disorders e.g. insomnia, Addiction, History of intake of any drug that affects sleep cognition e.g. antidepressants.

Outcome results