Pectoralis-serratus interfascial plane block vs. paravertebral block for acute post-mastectomy pain

In modified radical mastectomy, does Pectoralis-serratus interfascial plane block, compared to paravertebral block, reduce postoperative opioid consumption?

Status

Completed

Phases

Unknown

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12615000669594

Enrollment

Registered

2015-06-29

Start date

2013-11-25

Completion date

2015-05-27

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

pectoralis –serratus interfascial plane block (Pecs II block) in patients scheduled for MRM and axillary evacuation was compared with thoracic paravertebral block in terms of duration of analgesia, consumption of morphine and intensity of pain in the first 24 postoperative hours.

Interventions

Before induction of anesthesia (pre-incision), for group PS, we will give pectoralis-serratus interfascial plane block, in which we will inject 10 ml of bupivacaine 0.25% between pectoralis major and minor muscles around the pectoral nerve. and another 20 ml of bupivacaine 0.25% between pectoralis minor and serratus anterior muscles at the level of rib 4 under ultrasonographic guidence

Study design

Allocation

Randomised controlled trial

Primary purpose

Treatment

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

Adult women, American Society of Anesthesiologists (ASA) physical status class I–III, scheduled for unilateral modified radical mastectomy (MRM) with axillary evacuation

Exclusion criteria

The exclusion criteria included patients with a known allergy to bupivacaine or morphine, bleeding disorders, anatomical abnormalities, infection in the paravertebral region, pregnancy, breast feeding, severe obesity (body mass index >35 kg/m2), a history of drug or alcohol abuse and patients suffering from chronic pain or regularly receiving analgesics.

Outcome results