None listed
Conditions
Brief summary
The aim of this stydy is to compare the effects of volume-controlled and pressure-controlled ventilation on cardiac output changes in patients undergoing robotic assisted gynecologic surgery in steep Trendelenburg position. Hypothesis: PCV may be a more effective method for maintaining more stable haemodynamics.
Interventions
Mechanical ventilation mode:
PCV is an alternative mode of ventilation to VCV that is widely used in patients with elevated intraabdominal pressure and it has been shown to improve arterial oxygenation and decrease the peak airway pressure because of its decelerating inspiratory flow.
Mechanical ventilation will be administered continuously from induction of anesthesia until extubation. In the pressure-controlled group, the peak airway pressure not exceeding 35 cmH2O will be set to provide a t
Mechanical ventilation mode: PCV is an alternative mode of ventilation to VCV that is widely used in patients with elevated intraabdominal pressure and it has been shown to improve arterial oxygenation and decrease the peak airway pressure because of its decelerating inspiratory flow. Mechanical ventilation will be administered continuously from induction of anesthesia until extubation. In the pressure-controlled group, the peak airway pressure not exceeding 35 cmH2O will be set to provide a tidal volume of 8 ml/kg, with and I:E ratio of 1:1,5. The respiratory rate will be adjusted to obtain an end-tidal CO2 of 35-40 cmH2O to be started with a respiratory rate of 12/min.
Sponsors
Sariyer Hamidiye Etfal Training and Research Hospital
Study design
Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Prevention
Masking
Open (masking not used)
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Healthy volunteers
No
Inclusion criteria
ASA physical status I-II Robotic gynaecologic surgery patients
Exclusion criteria
Valvular heart disease Abnormal regional wall contraction in echocardiography Pericardial disease Dilated cardiomyopathy Left atrial dialtation Left ventricular dilatation Obstructive/restrictive lung disease Body mass index>30 Eosophageal disease/dysphagia Blood loss leading more than %10 decrease in MAP
Outcome results
None listed