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A multi-centre prospective observational study of simultaneous pulse oximeter and arterial oxygen saturation recordings in Intensive Care Unit patients.

In Intensive Care Unit patients requiring an arterial blood gas, a comparison between arterial oxygen saturation and pulse oximetry saturation measurements.

Status
Completed
Phases
Unknown
Study type
Observational
Source
ANZCTR
Registry ID
ACTRN12615000623594
Enrollment
400
Registered
2015-06-16
Start date
2015-06-10
Completion date
2016-04-26
Last updated
2021-06-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Pulse oximetry is commonly used in the clinical setting to guide oxygen therapy . The purpose of this study is to investigate the level of agreement between pulse oximeter measured oxygen saturations and arterial blood gas measured oxygen saturations (the gold standard for oxygen saturation measurement) in Australian and New Zealand Intensive Care Units.

Interventions

Evaluation of simultaneous pulse oximetry (SpO2) and arterial blood gas (ABG) measured oxygen saturation (SaO2) values recorded in ICU patients. The paired SpO2 value will be recorded at least 2 hours after admission to ICU, to allow for adjustments in oxygen therapy to become in-line with standard ICU practice for oxygen administration. Where possible, paired measurements will be done during the earliest arterial blood gas (ABG) taken after at least 2 hours of admission. A single set of pair

Evaluation of simultaneous pulse oximetry (SpO2) and arterial blood gas (ABG) measured oxygen saturation (SaO2) values recorded in ICU patients. The paired SpO2 value will be recorded at least 2 hours after admission to ICU, to allow for adjustments in oxygen therapy to become in-line with standard ICU practice for oxygen administration. Where possible, paired measurements will be done during the earliest arterial blood gas (ABG) taken after at least 2 hours of admission. A single set of paired measurements will be taken per patient.

Sponsors

MRINZ
Lead SponsorCharities/Societies/Foundations

Eligibility

Sex/Gender
All
Age
16 Years to No maximum
Healthy volunteers
No

Inclusion criteria

Four hundred patients with routine oxygen saturation monitoring and routine ABG measurements as part of their clinical care at Wellington Regional Hospital and Austin Hospital ICUs.

Exclusion criteria

1. Diagnosis of methaemoglobinemia or prior use of intravenous dye during this admission(e.g. methylene blue). 2. Diagnosis of CO poisoning. 3. Age under 16 years. 4. Patients previously recruited to the study with paired SpO2 and SaO2 values successfully recorded. 5. Any other condition which, at the investigator’s discretion, is believed may present a safety risk or impact upon the feasibility of the study or the interpretation of the study results.

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026