None listed
Conditions
Brief summary
40 participants will be recruited to complete a 12-week exercise training intervention which consists of either high-intensity intermittent exercise or continuous moderate-intensity exercise on a cycle ergometer. This study aims to determine the effect of exercise training on the changes in insulin sensitivity and the immune system as a result of a training adaptation over the 12-week period. This will be a parallel randomised group design which will include male participants between the age of 18-44 years old who are overweight (BMI greater than or equal to 25 kg/m2) but otherwise healthy (no previous history of type 2 diabetes or other immune-related diseases).
Interventions
Exercise training consisting of either:
High intensity exercise (HIT) or continuous moderate-intensity (CME)
HIT - 6 bouts of high-intensity intermittent exercise @ 100% VO2max, on a stationary cycle ergometer with a work-to-rest ratio of 1:4 over a period of 30-minutes. Active recovery consists of cycling @ 50% VO2max and performance will be monitored on the software associated with the cycle ergometer.
CME - Moderate-intensity exercise @ 60% VO2max over a period of 30-minutes on a stationar
Exercise training consisting of either: High intensity exercise (HIT) or continuous moderate-intensity (CME) HIT - 6 bouts of high-intensity intermittent exercise @ 100% VO2max, on a stationary cycle ergometer with a work-to-rest ratio of 1:4 over a period of 30-minutes. Active recovery consists of cycling @ 50% VO2max and performance will be monitored on the software associated with the cycle ergometer. CME - Moderate-intensity exercise @ 60% VO2max over a period of 30-minutes on a stationary cycle ergometer. 3 sessions per week 12 weeks Group session The researcher will administer the intervention. Dr. Timothy Fairchild is an ESSA Accredited Exercise Physiologist and Aaron Raman is a PhD student in exercise science. Exercise adherence will be noted with an exercise log.
Sponsors
Murdoch University
Study design
Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Open (masking not used)
Eligibility
Sex/Gender
Male
Age
18 Years to 44 Years
Healthy volunteers
No
Inclusion criteria
BMI > 25 Sedentary
Exclusion criteria
Previously diagnosed with Type 2 diabetes Have an inflammatory disease Taking medication that may affect blood pressure, glucose control and/or cholesterol.
Outcome results
None listed