Skip to content

A Randomized Controlled Trial of Self-regulated Constraint-induced Movement Therapy to promote functional regain in Subacute Stroke Patients

A Randomized Controlled Trial of Self-regulated Constraint-induced Movement Therapy as compared with conventional occupational therapy to promote functional regain in Subacute Stroke Patients

Status
Completed
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12615000604505
Enrollment
81
Registered
2015-06-09
Start date
2008-09-10
Completion date
2010-10-12
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Emerging research suggests the use of self-regulation (SR) strategies at improving functional regain in patients with brain injury. SR is proposed to produce an added effect to the effective constraint-induced movement therapy (CIMT). This study aimed to examine the efficacy of a self-regulated CIMT program (SR-CIMT) for function regain of patients with sub-acute stroke. It was hypothesized that participants receiving the combined treatment (SR and CIMT) would have a better functional regain.

Interventions

Self-regulated constraint-induced movement therapy (SR-CIMT) - participants' non-hemiplegic arm was restrained in a mitt for 4 hours every day, 2 weeks, 5 days a week (therapy days) (CIMT) (the same CIMT protocol as in the CIMT group described under 'comparator/control treatment'); participants were taught using the self-regulation (SR) strategy to relearn the tasks; SR strategy involved participants self-reflecting on their abilities and deficits in performing the tasks, identifying problems an

Self-regulated constraint-induced movement therapy (SR-CIMT) - participants' non-hemiplegic arm was restrained in a mitt for 4 hours every day, 2 weeks, 5 days a week (therapy days) (CIMT) (the same CIMT protocol as in the CIMT group described under 'comparator/control treatment'); participants were taught using the self-regulation (SR) strategy to relearn the tasks; SR strategy involved participants self-reflecting on their abilities and deficits in performing the tasks, identifying problems and solutions in achieving the most independence in the tasks, and then actually carrying out the tasks. There were 10 tasks to practice in total, they included fold laundry, put clothes on hanger, brush teeth, dress upper garment, dress lower garment in week one; and use telephone, prepare a cup of tea, sweep floor, wash towel, wash dishes in week two. In the 4 hours when the participants had their non-hemiplegic arm in the restrain, they received one hour therapist-guided training using SR strategy on task relearning as described above. Therefore, all participants received 10 one-hour therapist-guided training sessions (daily on weekdays, total two weeks). The intervention was delivered by occupational therapist. For the rest of the 3 hours in the restrain, the participants' wearing of the restrain was monitored by the nursing staff in the ward.

Sponsors

The Hong Kong Polytechnic University
Lead SponsorUniversity

Study design

Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Blinded (masking used) (Subject, Outcomes Assessor)

Eligibility

Sex/Gender
All
Age
60 Years to No maximum
Healthy volunteers
No

Inclusion criteria

Patients receiving in-patient rehabilitation post-stroke were recruited from a rehabilitation hospital. Patients were eligible if they: (1) had sustained an ischemic type stroke with lesion in the primary or motor cortical areas resulting in hemiplegia, (2) had stroke onset of less than 3 months, (3) were aged above 60, (4) had 10 degree active extension in metacarpophalangeal joint and interphalangeal joint, 20 degree active extension of wrist joint.

Exclusion criteria

(1) had excessive spasticity in the affected limb, as defined by a score of 2 or more on the Modified Ashworth Scale, (2) had excessive pain in the affected limb, as defined by a score 4 or more using a Visual Analog Scale, (3) had a score below 19 on the Mini-Mental Status Examination (MMSE), and (4) had diagnosed of depression according to DSM-IV criteria.

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026