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Development of a clinical prediction rule to improve peripheral intravenous cannulae first attempt success in the Emergency Department and reduce post insertion failure rates. An investigation of Vascular Access Decisions in the Emergency Room: The VADER study.

Evaluating risk factors for peripheral intravenous cannula (PIVC) insertion failure among Emergency Department clinicians performing PIVC insertion in adult patients and effect on first-time insertion success and PIVC dwell time: The VADER study.

Status
Completed
Phases
Unknown
Study type
Observational
Source
ANZCTR
Registry ID
ACTRN12615000588594
Acronym
The VADER Study
Enrollment
975
Registered
2015-06-04
Start date
2015-06-19
Completion date
2016-05-11
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Peripheral intravenous cannula (PIVC) insertion is the one of the most common clinical interventions performed in the Emergency Department (ED) worldwide. Improving the first time insertion success rate and dwell time of PIVCs inserted in EDs can prevent repeat needle insertions. A number of factors have been identified as predictor’s of insertion failure and premature device failure. However, none have focused on the patient's journey with PIVC from ED to hospital admission. Purpose: This study proposes to determine the predictors of first time PIVC insertion success in ED and risk factors for PIVC failure for ED patients admitted to the hospital wards. Methods: A prospective observational cohort study of PIVC insertions in a patient population presenting to ED, with follow-up of subsequent admissions to hospital wards. Data in relation to clinician and patient risk factors will be collected from medical records and observations, as well as device information. Multivariable regression analyses will be sued to identify factors associated with insertions success and PIVC failure Results: The projected sample size n=1000 PIVC insertions will provide sufficient power to determine the association between risk factors and first-time insertion success and premature device failure. Conclusion: This study will provide new evidence to improve insertion success rates in ED and identify strategies to reduce premature device failure for patients admitted to hospital wards with PIVC.

Interventions

The study proposes to determine the factors surrounding peripheral intravenous cannula (PIVC) insertion to identify best practices to promote first-time insertion success, and reduce repeat PIVC insertion for patients admitted to the hospital wards. A prospective observational study of clinicians performing PIVC insertion in a patient population presenting to ED, with follow-up of any subsequent admissions to hospital wards. Observations include the insertion of PIVC in ED. Patients who are adm

The study proposes to determine the factors surrounding peripheral intravenous cannula (PIVC) insertion to identify best practices to promote first-time insertion success, and reduce repeat PIVC insertion for patients admitted to the hospital wards. A prospective observational study of clinicians performing PIVC insertion in a patient population presenting to ED, with follow-up of any subsequent admissions to hospital wards. Observations include the insertion of PIVC in ED. Patients who are admitted with the observed ED PIVC will be followed up and observed daily until the ED PIVC is removed. All observations and questions we propose are underpinned by scientific literature and have undergone face and content validity indexing.

Sponsors

Sir Charles Gairdner Emergency Medicine
Lead SponsorHospital

Eligibility

Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

All clinical staff who place PIVCs as part of their role in the Emergency Department, and who consent to participate. All patients >18 years will be approached. We will attempt to observe all patient types and as such a waiver of consent has been granted. However, patients with the capacity to understand what the researchers are doing will be verbally informed as to what we intend to observe. Family members present with patients who do not have the capacity to understand will also be informed. If either the patient or family members advocating on behalf of a patient decline to have a PIVC procedure observed, they will not be coerced into taking part.

Exclusion criteria

Patients under 18 years of age. Clinician participants who decline to provide consent. Patients with the capacity to understand and decline to take part and/or family advocating for patients who decline on the patient's behalf.

Outcome results

None listed

Source: ANZCTR · Data processed: Mar 2, 2026