None listed
Conditions
Brief summary
Total knee replacement (TKR) is a common operation for knee arthritis. Effective pain control is important in post-operative recovery and rehabilitation. Recent studies have shown that injections of a mixture of medications into the tissues around the knee at the time of surgery can decrease the amount of pain experienced after surgery, leading to improved rehabilitation and a shorter hospital stay. We would like to determine if pain is better controlled with injections into the tissues around the knee joint (periarticular), compared to injections into the joint itself (intraarticular) at the time of total knee replacement surgery.
Interventions
One hundred and forty two consecutive patients undergoing total knee arthroplasty were enrolled. Patients were divided into 2 groups, a periarticular infiltration group (Group A) and an intraarticular injection group (Group B). Both groups received the same infiltrate – a combination of 30mg ketorolac, 500mcg of adrenaline, and 300mg of ropivacaine, and normal saline.
In Group A patients, the 150mL was infiltrated after implantation of the prosthesis, prior to insertion of the polyethylene lin
One hundred and forty two consecutive patients undergoing total knee arthroplasty were enrolled. Patients were divided into 2 groups, a periarticular infiltration group (Group A) and an intraarticular injection group (Group B). Both groups received the same infiltrate – a combination of 30mg ketorolac, 500mcg of adrenaline, and 300mg of ropivacaine, and normal saline. In Group A patients, the 150mL was infiltrated after implantation of the prosthesis, prior to insertion of the polyethylene liner. Of this, 50mL was infiltrated into the posterior capsule and intercondylar area; 50mL was infiltrated into the anterior capsule, the collateral ligaments and along the femur and tibia; and the remaining 50mL was infiltrated into subcutaneous tissue following closure of the capsule. Group B patients had all of the 150ml injected intraarticularly after closure of the wound.
Sponsors
Fremantle Hospital
Study design
Allocation
Non-randomised trial
Intervention model
Other
Primary purpose
Treatment
Masking
Blinded (masking used) (Subject)
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
adult patients waitlisted for primary total knee replacement for osteoarthritis.
Exclusion criteria
allergy or intolerance to study drugs, known inability to receive spinal anaesthesia, and planned bilateral knee surgery. secondary exclusion criteria: history of regular opioid use, concurrent psychiatric illness, serious medical comorbidities that might prolong hospital admission, and coagulation disorders
Outcome results
None listed