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Does Saphenous Nerve Block in Hamstring Anterior Cruciate Ligament Reconstruction Affect Postoperative Pain? A Randomised Controlled Trial

Effect of saphenous nerve block versus no block on patient perception of pain in patients undergoing ACL reconstruction with ipsilateral hamstring autograft

Status
Completed
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12615000482561
Acronym
ACL block study
Enrollment
60
Registered
2015-05-15
Start date
2015-05-22
Completion date
2015-11-30
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Reconstruction of anterior cruciate ligament (ACL) of the knee is a common procedure. Perioperative analgesia for ACL reconstruction using hamstring autograft can be achieved with multimodal analgesia +/- addition of nerve block. Saphenous nerve block is commonly used in our practice for patients undergoing ACL reconstruction. Performing a saphenous nerve block adds cost, time and complications (overall rare) to the overall procedure with a perceived benefit of reduced opiate requirement and increased patient comfort. The benefit of saphenous nerve block for hamstring autograft ACL reconstruction has not been established in the literature. We hypothesize that saphenous nerve block in ACL reconstruction with hamstring autograft does not improve patient comfort.

Interventions

Saphenous nerve block for patients undergoing ACL reconstruction with hamstring autograft. This involves 15cc 0.5% Ropivacaine (75mg) with an ultrasound guided approach picking a spot 10 cm above the patella, after general anaesthesia. Both groups will receive multimodal analgesia. This includes IV paracetamol 1g 20min before the end of the case, and Parecoxib 40mg IV during the case. Surgeons will infiltrate hamstring site and knee joint with Ropivacaine 2mg/kg and 10mg of Morphine into the k

Saphenous nerve block for patients undergoing ACL reconstruction with hamstring autograft. This involves 15cc 0.5% Ropivacaine (75mg) with an ultrasound guided approach picking a spot 10 cm above the patella, after general anaesthesia. Both groups will receive multimodal analgesia. This includes IV paracetamol 1g 20min before the end of the case, and Parecoxib 40mg IV during the case. Surgeons will infiltrate hamstring site and knee joint with Ropivacaine 2mg/kg and 10mg of Morphine into the knee joint (intra-articular).

Sponsors

Unisports Ltd
Lead SponsorCommercial sector/Industry

Study design

Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Open (masking not used)

Eligibility

Sex/Gender
All
Age
16 Years to 80 Years
Healthy volunteers
No

Inclusion criteria

All patients undergoing ACL reconstruction with ipsilateral hamstring autograft at our practice.

Exclusion criteria

a. Previous ligamentous ipsilateral knee surgery b. Concurrent surgery on contralateral limb c. Any other graft use d. Lack of adequate English as this would inhibit VAS score e. Allergy or contraindication to Tramadol, Morphine, Fentanyl, Parecoxib, Ropivacaine, Postop NSAIDS, Paracetamol f. Neurological disease involving peripheral nerves g. Chronic pain issues h. Drug addiction or tolerance with analgesics i. Age less than 16

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026