None listed
Conditions
Brief summary
The purpose of this study is to determine the acceptability and preference of permethrin-treated and non-treated clothing in rubber plantations in Myanmar. The information obtained from this assessment will assist policy makers to determine which type of clothing is most appropriate for prevention of outdoor transmission of malaria. Information on clothing durability, washing, colour, texture, size, fabric and size preference, willingness to pay will be collected. Feedback provided by participants will guide future promotional and educational messages that accompany clothing distribution.
Interventions
Permethrin insecticide-treated (ITC) and non-treated clothing (NTC) will be trialled and assessed for their acceptability among a randomly selected sample of rubber tappers in Mon State, Myanmar.
The ITC and NTC both consist of a long-sleeved cotton shirt and long cotton pants purchased from a local market vendor in Myanmar. The ITC has been treated with a long-lasting permethrin formulation using a factory proprietary method in China. The NTC is untreated but otherwise identical to the ITC. T
Permethrin insecticide-treated (ITC) and non-treated clothing (NTC) will be trialled and assessed for their acceptability among a randomly selected sample of rubber tappers in Mon State, Myanmar. The ITC and NTC both consist of a long-sleeved cotton shirt and long cotton pants purchased from a local market vendor in Myanmar. The ITC has been treated with a long-lasting permethrin formulation using a factory proprietary method in China. The NTC is untreated but otherwise identical to the ITC. The clothing is intended to be worn by the rubber tappers during their nighttime work, for approximately 10-12 hours per day. The clothing is washable and all enrolled participants will receive care instructions and a calendar on which to record the days they wash the clothing. Randomly selected rubber tappers will be cluster randomized to one of the two assessment groups – Arms 1 and 2. Each arm will be assigned ITC and NTC in a crossover design to trial. Each rubber tapper will trial the two different clothing types assigned to their group for approximately 14 days each. Then, the second clothing type trialled will be continued for a further 6 weeks, that is- participants in Arms 1 and 2 will continue with NTC and ITC, respectively, for six weeks after four weeks of wearing both types of clothing. As this is an acceptability and preference study, no wash-out period was deemed necessary. STUDY DESIGN OUTLINE: Arm 1 - to trial ITC then NTC Arm 2 - to trial NTC then ITC
Sponsors
Department for International Development (DFID)
Study design
Allocation
Randomised controlled trial
Intervention model
Crossover
Primary purpose
Prevention
Masking
Blinded (masking used) (Subject, Caregiver)
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
Adult (greater than or equal to 18 years.) Head of the household and/or a fulltime rubber tapper. Capable of giving informed consent to participate in the study. Resident in the study area for at least 5 months from enrollment (until May 2015).
Exclusion criteria
Are likely to be absent from the plantation during the study period. Would be unable or unlikely to comply with the study protocol. History of skin allergy or eczema, or have had a previous adverse reaction to the use of treated bednets other than those that were minor and transient. Currently pregnant or breastfeeding.
Outcome results
None listed