None listed
Conditions
Brief summary
General anaesthesia, whilst very safe, has some undesirable side effects. Two of these, a fall in body temperature and a fall in blood pressure, are usually very mild and require little treatment. Occasionally, more severe changes can result requiring significant intervention by the anaesthetist. Whilst prewarming of patients prior to surgery is sometimes employed to reduce the drop in body temperature seen with anaesthesia, it is not known whether this warming may also help reduce the fall in blood pressure. Warming patients results in dilation of blood vessels, with some of the circulating blood volume then moving into more peripheral tissues. This is similar to the process that happens under anaesthesia, with the relaxation of blood vessels caused by anaesthetic drugs resulting in lowered blood pressure. This is usually mild and easily correctable with medications and intravenous fluid administered by the anaesthetist, though occasionally can be more serious. This study aims to answer the question of whether prewarming patients may reduce the fall in blood pressure seen with the onset of anaesthesia, due to blood vessels already being dilated, and hence reduce the need for intervention by the anaesthetist.
Interventions
Sponsors
Study design
Eligibility
Inclusion criteria
1. Neurosurgical patients aged 18 years and over 2. Craniotomy for any indication 3. American Society of Anesthesiologists’ (ASA) physical status 1-3
Exclusion criteria
1. Inadequate English comprehension due to a language barrier, cognitive deficit or intellectual disability 2. Significant cardiorespiratory impairment (i.e. ASA 4-5 patients) 3. Severe hypertension (systolic BP > 180 mmHg, diastolic BP > 110 mmHg in the operating suite admission bay) 4. Antihypertensive therapy with ACE inhibitor/angiotensin II receptor antagonist if administered on the day of surgery 5. Secondary hypertension (e.g. renal artery stenosis, phaeochromocytoma, Cushing's syndrome) 6. Temperature > 37.5 degrees Celcius at baseline 7. Thyroid dysfunction 8. Otitis media/externa (preventing accurate tympanic membrane temperature measurement)