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Cervical spinal manipulation versus thoracic spinal manipulation on peripheral neural features and grip strength in subjects with chronic mechanical neck pain: A randomized controlled trial.

To compare the immediate effects of cervical and thoracic spinal manipulative therapy (SMT) on neural mechanosensitivity of upper limb nerve trunks and grip strength in patients with chronic neck pain (NP).

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12615000412538
Enrollment
88
Registered
2015-05-01
Start date
2015-04-21
Completion date
Unknown
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Widespread sensory changes have been observed in some subgroups of mechanical NP, although this is still a matter of discussion we hypothesized that, in decreasing neural mechanosensitivity will have a positive impact in parameters that are strongly related to the functionality of the cervical and thoracic spine. So after the spinal manipulation, we will find an immediate increase in neural mechanosensitivity and grip strength.

Interventions

The sample included subjects with mechanical non-specific NP, that were randomly distributed into three groups. The cervical group received a high-velocity low amplitude (HVLA) spinal manipulation over the lower cervical spine (C7), the thoracic group underwent a HVLA spinal manipulation over the upper thoracic spine (T3), whereas the placebo group (PG) received a sham-manual contact. Measurements were taken before intervention and immediately afterwards of the pressure pain threshold over the m

The sample included subjects with mechanical non-specific NP, that were randomly distributed into three groups. The cervical group received a high-velocity low amplitude (HVLA) spinal manipulation over the lower cervical spine (C7), the thoracic group underwent a HVLA spinal manipulation over the upper thoracic spine (T3), whereas the placebo group (PG) received a sham-manual contact. Measurements were taken before intervention and immediately afterwards of the pressure pain threshold over the median, ulnar and radial nerves and free-pain grip strength with a hydraulic dynamometer.The intervention performed a physiotherapist and lasted five minutes in a single session.

Sponsors

University of Seville (Spain)
Lead SponsorUniversity

Study design

Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Blinded (masking used)

Eligibility

Sex/Gender
All
Age
20 Years to 50 Years
Healthy volunteers
No

Inclusion criteria

(a) age between 20 and 50 years old; (b) NP (grades I or II) of at least 12 weeks of duration; and (c) a positive response to the ULNT of the median nerve (ULNT-1) in at least one upper limb.

Exclusion criteria

Subjects who had one or more of the following conditions were excluded: (a) any contraindication to SMT (bone pathology, tumors, inflammatory disease...); (b) current use of any drugs or medication; (c) mechanical NP secondary to whiplash, congenital or acquired torticollis, rheumatoid arthritis, advanced cervical osteoarthritis and / or cervical myelopathy; (d) previous history of joint disease, tendinitis, severe trauma or surgery in the upper extremity and / or cervical spine; (e) cervicobrachial radiculalgia associated with herniation or disc protrusion at lower cervical spine; (f) diagnosis of carpal tunnel syndrome or previous surgery at this level; (g) serious hormonal imbalance, history of diabetes and / or hypothyroidism; (h) having received SMT in the eight weeks before data collection; (i) pregnant or menopausal women.

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026