None listed
Conditions
Brief summary
Venous cannulation via peripheral intravenous catheters (PIVC) is the simplest and most frequently used method for drug, fluid and blood product administration. Researchers estimate that up to 70% of patients in acute care hospitals require a PIVC. However, PIVC are associated with inherent complications which can be mechanical or infectious. Failure rates of these devices is unacceptably high, affecting up to 40% of patients receiving this therapy. Of these, 30% failed due to occlusion and infiltration (fluids into surrounding tissues) meaning patients had to have the PIVC replaced, which has implications for patient comfort, therapy and health care costs.There have been a range of strategies developed to prevent or reduce PIVC related complications including flushing regimes to maintain PIVC patency. However, current flushing practice is widely varied, with poor outcomes. There is little evidence that flushing of PIVC is actually happening in practice. To achieve best and evidence based practice it imperative that trial research is conducted to establish the best regime for maintaining PIVC patency. The study aims to establish the feasibility of conducting a four arm, factorial, randomized trial evaluating the efficacy and cost effectiveness of different flushing frequencies and volumes in a paediatric population.
Interventions
Participants will have their peripheral cannula (PIVC) flushed with one of the following, until the patient requires PIVC removal, by the nurse providing care for the patient:
1. low frequency IV flush 0.9% Sodium Chloride every 24h, low volume 3mL
2. low frequency IV flush 0.9% Sodium Chloride every 24h , high volume 10mL
3. high frequency IV flush 0.9% Sodium Chloride every 6h, low volume 3mL
4. high frequency IV flush 0.9% Sodium Chloride every 6h, high volume 10mL
AND
pre and post medicatio
Participants will have their peripheral cannula (PIVC) flushed with one of the following, until the patient requires PIVC removal, by the nurse providing care for the patient: 1. low frequency IV flush 0.9% Sodium Chloride every 24h, low volume 3mL 2. low frequency IV flush 0.9% Sodium Chloride every 24h , high volume 10mL 3. high frequency IV flush 0.9% Sodium Chloride every 6h, low volume 3mL 4. high frequency IV flush 0.9% Sodium Chloride every 6h, high volume 10mL AND pre and post medication administration.
Sponsors
Griffith University
Study design
Allocation
Randomised controlled trial
Intervention model
Factorial
Primary purpose
Prevention
Masking
Open (masking not used)
Eligibility
Sex/Gender
All
Age
No minimum to 18 Years
Healthy volunteers
No
Inclusion criteria
Peripheral intravenous catheter inserted for clinical care Informed consent to participate
Exclusion criteria
Patients < 5kg or on fluid restrictions Planned removal of Peripheral intravenous catheter within next 24hrs Previous enrolment in the current study
Outcome results
None listed