Identification of clinical data useful to predict the development of prolonged symptoms after a concussion, at the time of initial assessment in the Emergency Department.

Conditions

None listed

Brief summary

The Predictors of Post Concussive Syndrome Protocol that we are developing concerns a study on the derivation and validation of a clinical prediction rule for PCS in children aged 5 to 18 years, who present to the ED for concussion. In order to assist clinicians in identifying patients at high risk of PCS, who will benefit from a closer follow up and early referral to a dedicated concussion clinic, we set out to derive and validate a clinical prediction rule based on pre-injury and injury-related data to be used in the ED.

Michael Takagi, Franz E Babl, Nicholas R. Anderson, Silvia Bressan, Cathriona J Clarke et al. (19 authors)

BMJ Open2019-02-0118 citations

10.1136/bmjopen-2018-022098

Protocol for a prospective, longitudinal, cohort study of postconcussive symptoms in children: the Take C.A.Re (Concussion Assessment and Recovery Research) study

Silvia Bressan, Michael Takagi, Vicki Anderson, Gavin A Davis, Ed Oakley et al. (12 authors)

BMJ Open2016-01-0128 citations

10.1136/bmjopen-2015-009427

Interventions

We will examine factors that predict post-concussive syndrome in children aged 5-18. We will assess children at presentation to the emergency department and again at 1-4 days, 2-weeks, 1- month, and 3-months post-injury. We will be observing post-concussive symptoms at each time point. This can include a broad range of symptoms, such as: somatic (eg, headache, vomiting); cognitive (eg, feeling like in fog); emotional (eg, lability); Physical signs (eg, loss of consciousness, amnesia); Behavi

We will examine factors that predict post-concussive syndrome in children aged 5-18. We will assess children at presentation to the emergency department and again at 1-4 days, 2-weeks, 1- month, and 3-months post-injury. We will be observing post-concussive symptoms at each time point. This can include a broad range of symptoms, such as: somatic (eg, headache, vomiting); cognitive (eg, feeling like in fog); emotional (eg, lability); Physical signs (eg, loss of consciousness, amnesia); Behavioural changes (eg, irritability); Cognitive impairment (eg, slowed reaction times); Sleep disturbance (eg, insomnia).

Eligibility

Sex/Gender

All

Age

5 Years to 18 Years

Healthy volunteers

No

Inclusion criteria

Patients aged 5-18 years who present to the ED for a concussion sustained in the previous 48 hours

Exclusion criteria

Intubated patients on arrival to the ED Need of neurosurgical operative intervention or general anaesthesia for injury management Presence of structural/haemorrhagic intracranial injury on CT scan brain Clinical evidence of CSF leak Intellectual disability with inability to complete the testing measures. Injury resulting from child abuse or assault Alcohol or drug intoxication at time of presentation to the ED Insufficient understanding of English as per assessment by the treating physician/research assistant in the ED Multiple trauma No clear history of trauma as primary event (eg, seizure, syncope or migraine as primary event)

Outcome results