None listed
Conditions
Brief summary
Update The research project is comparing different devices for giving oxygen during the start of an anaesthetic. The different devices are called nasal prongs and nasopharyngeal cannula. Nasal prongs and nasopharyngeal cannula are already approved in Australia to supply Oxygen to patients in hospital. All participants will receive Oxygen through a face mask before they are put to sleep for an operation. In addition, participants may receive additional Oxygen through nasal prongs or nasopharyngeal cannula. You will then be given anaesthetic medication and will go to sleep as normal. In this study, we would like to see how patients’ Oxygen levels in their throat change once they are asleep, enabling us to compare the different devices in terms of their effectiveness and the extent to which they can increase oxygen levels. Our hypothesis is that each of the devices will increase Oxygen levels and we aim to determine if there is any difference between these two devices with respect which may be more effective at delivering Oxygen for this purpose.
Interventions
Our study compares the application of oxygen via nasal prongs to nasopharyngeal cannula during the period of apnoea, prior to intubation.
Nasal prongs are a non-invasive means of delivering oxygen. They are comprised of a lightweight tube with two small prongs, each of which enters the nostrils, through which a mixture of oxygen and air is delivered. It is connected to an Oxygen supply.
Nasopharyngeal cannula is a longer, flexible tube which is passed through a single nostril, further into the
Our study compares the application of oxygen via nasal prongs to nasopharyngeal cannula during the period of apnoea, prior to intubation. Nasal prongs are a non-invasive means of delivering oxygen. They are comprised of a lightweight tube with two small prongs, each of which enters the nostrils, through which a mixture of oxygen and air is delivered. It is connected to an Oxygen supply. Nasopharyngeal cannula is a longer, flexible tube which is passed through a single nostril, further into the upper airway until the tip comes to rest at the oropharyngeal inlet. This is also non-invasive and is connected to an oxygen supply so that air and oxygen can be delivered through it. We will apply the chosen device to our patients before anaesthetic induction and provide normal pre-oxygenation. Oxygen will then run through the devices at 15Litres/minute. This will flow for three minutes, after the patient stops breathing and before intubation is attempted. Normally, no devices are applied to the patient during this period. The concentration of oxygen (Fi02) at the pharyngeal inlet is measured just prior to intubation. We will compare these values.
Sponsors
Department of Anaesthetics, Southern Health
Study design
Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Prevention
Masking
Open (masking not used)
Eligibility
Sex/Gender
All
Age
16 Years to No maximum
Healthy volunteers
No
Inclusion criteria
Inclusion criteria include patient undergoing surgery at Southern Health, who are over or equal to 16 years of age, require intubation and paralysis for their surgery, who have pre-operative oxygen saturations >94% on room air and provide their informed consent to be included in the study.
Exclusion criteria
Exclusion criteria include patients less than 16 years of age, pregnant patients and those who have oxygen saturations on room air of less than 94%.
Outcome results
None listed