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Neurocognitive training for traumatic brain injury: cognitive, behavioural, and electrophysiological outcomes.

Does neurocognitive training improve cognitive, behavioural, and electrophysiological outcomes in adults with TBI compared to a waitlist control group?

Status
Withdrawn
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12615000251527
Enrollment
40
Registered
2015-03-19
Start date
2015-03-24
Completion date
Unknown
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

The primary purpose of the study is to assess the efficacy of a neurocognitive training program for improving executive function and arousal state modulation in adults with traumatic brain injury. It is expected that compared to a waitlist control, those who complete the training will show improvements on a rang of cognitive and behavioural measures of executive function, as well as improvement in their ability to regulate arousal state of the brain (brain activity measured by EEG).

Interventions

The Focus Pocus (version 2) neurocognitive training software was developed by NeuroCog Proprietary Limited incorporating intellectual property licensed from UOW. The software consists of a series of wizard-themed, computerised, mini-games targeting inhibitory control (IC), working memory (WM) and state control (SC). During use of the software, participants are required to wear a portable EEG headset; the NeuroSky MindWave. The headset records EEG from a single, dry, sensor resting on the for

The Focus Pocus (version 2) neurocognitive training software was developed by NeuroCog Proprietary Limited incorporating intellectual property licensed from UOW. The software consists of a series of wizard-themed, computerised, mini-games targeting inhibitory control (IC), working memory (WM) and state control (SC). During use of the software, participants are required to wear a portable EEG headset; the NeuroSky MindWave. The headset records EEG from a single, dry, sensor resting on the forehead referenced to an ear-clip electrode. During SC games, participants are instructed to ‘focus’, ‘relax’ or induce a state of ‘zen' (i.e. focused and relaxed), and the corresponding EEG pattern is used to control elements of the game (e.g. the speed of the player in a broomstick race). During WM and IC games, EEG is passively monitored and categorised according to attention level during the game, with attention level then used as a multiplier for game points. Game difficulty adapts constantly based on performance to ensure that games are challenging but not too difficult. Participants receive on-screen feedback about performance following each game. In the present study, participants will be required to complete 25 sessions of the neurocognitive training, at a rate of 5 sessions per week. Each training session will consist of 6 SC, 4 WM, and 4 IC games, and will take approximately 20 minutes to complete. Participants will self-administer the training in their own homes, using their own personal computer or iOS device and a loan headset. Data regarding training compliance and performance will be sent to an online server, so that researchers can monitor progress.

Sponsors

University of Wollongong
Lead SponsorUniversity

Study design

Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Open (masking not used)

Eligibility

Sex/Gender
All
Age
18 Years to 50 Years
Healthy volunteers
No

Inclusion criteria

Sustained a TBI at least 6 months ago Subjective reports of cognitive impairment (attention, memory, executive function)

Exclusion criteria

Drug and alcohol disorders Psychiatric disorders, dementia or neurodegenerative disease Vision, hearing, motor or communication problems restricting use of computer software/hardware

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026