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A randomised repeated measures dietary intervention study to measure the effect of “Hayward” and “Sungold” kiwifruit on postprandial blood glucose (glycaemic) response relative to the response to a glucose reference dose, and the effect on glycaemic response of equi-carbohydrate partial exchange of kiwifruit for breakfast cereal, in healthy adult subjects.

A randomised repeated measures dietary intervention study to measure the effect of “Hayward” and “Sungold” kiwifruit on postprandial blood glucose (glycaemic) response relative to the response to a glucose reference dose, and the effect on glycaemic response of equi-carbohydrate substitution of kiwifruit for breakfast cereal, in healthy adult subjects.

Status
Completed
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12615000222549
Enrollment
20
Registered
2015-03-09
Start date
2015-01-05
Completion date
2015-01-30
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

This is a randomised repeated measures trial in which the interventions are a glucose reference, “Hayward” and “Sungold” kiwifruit, WeetBix breakfast cereal, and the breakfast cereal partially substituted by kiwifruit. The subjects (n = 15-20) will each receive all treatments with at least two days between treatments. They will be asked to consume each diet after an overnight fast and capillary blood glucose samples will be taken at intervals over a three hour period to allow a blood glucose response curve to be established, from which several characteristics of the response will be determined.

Interventions

Subjects will each consume six diets in random order, with at least two days between diets. The diets will be: 1. Glucose (reference) 40 g dissolved in water, 2. Weet Bix (amount providing 40 g available carbohydrate) 3. Gold kiwifruit (200 g, containing about 20 g cabohydrate) 4. Green kiwifruit (200 g, containing about 20 g cabohydrate) 5. Weet-Bix substituted on an equal glycaemic carbohydrate basis by 200 g “Hayward” kiwifruit (Total carbohydrate intake 40 g; Kiwifruit 200 g, Weet-Bix 30.9 g

Subjects will each consume six diets in random order, with at least two days between diets. The diets will be: 1. Glucose (reference) 40 g dissolved in water, 2. Weet Bix (amount providing 40 g available carbohydrate) 3. Gold kiwifruit (200 g, containing about 20 g cabohydrate) 4. Green kiwifruit (200 g, containing about 20 g cabohydrate) 5. Weet-Bix substituted on an equal glycaemic carbohydrate basis by 200 g “Hayward” kiwifruit (Total carbohydrate intake 40 g; Kiwifruit 200 g, Weet-Bix 30.9 g, water 120 ml) 6. Weet-Bix substituted on an equal glycaemic carbohydrate basis by 200 g “Sungold” kiwifruit (Total carbohydrate intake 40 g; Kiwifruit 200 g, Weet-Bix 27.06 g, water 120 ml). Subjects will be asked to consume diets after an overnight fast and the blood glucose response to the diets will be measured as changes from baseline in blood glucose concentrations measured by finger-prick capillary blood glucose analysis. The procedure is standard in measurement of the glycaemic index of foods. The subjects will consume two diets per week over a period of three weeks.

Sponsors

New Zealand Institute for Plant & Food Research Limited
Lead SponsorGovernment body

Study design

Allocation
Randomised controlled trial
Intervention model
Crossover
Primary purpose
Prevention
Masking
Open (masking not used)

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years
Healthy volunteers
Yes

Inclusion criteria

1. Subject between the ages of 18 and 65. 2. Subjects healthy adjudged by GHQ, past history, blood glucose response and HbA1c level. 3. Tolerant to kiwifruit. 4. Willing to adhere to the requirements of the study.

Exclusion criteria

1. Intolerance of kiwifruit 2. Glucose intolerance or HbA1c above the normal range.

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026