None listed
Conditions
Brief summary
This study will test two hypotheses and consist of two parts: 1. Part 1. The thickness of abdominal SCF, measured by ultrasound at 18-22 weeks gestation, predicts maternal outcomes (gestational diabetes, pregnancy-related hypertensive disorders, mode of delivery) and fetal outcomes (estimated fetal weight, birth outcome, gestational age, gender, weight, length, head circumference, large for gestational age, small for gestational age, intrauterine growth restriction). 2. Part 2. The thickness of abdominal SCF, measured by ultrasound at 18-22 weeks gestation, predicts the difficulty inserting an epidural, the difficulty palpating the landmarks of epidural insertion and the subcutaneous fat measured at lumbar interspace L3-4.
Interventions
Abdominal subcutaneous fat measured by ultrasound at 18-22 weeks gestation, as a measure of central adiposity.
Part 1: SCF measured at 18-22 weeks gestation will be analyzed against obesity-related pregnancy outcomes (maternal and fetal) to determine if it can be used to predict such outcomes. The observation period will last from the time the measurement is taken until the week after the fetus has been delivered.
Part 2. In women booked for elective caesarean section, the measurement of su
Abdominal subcutaneous fat measured by ultrasound at 18-22 weeks gestation, as a measure of central adiposity. Part 1: SCF measured at 18-22 weeks gestation will be analyzed against obesity-related pregnancy outcomes (maternal and fetal) to determine if it can be used to predict such outcomes. The observation period will last from the time the measurement is taken until the week after the fetus has been delivered. Part 2. In women booked for elective caesarean section, the measurement of subcutaneous fat taken at 18-22 weeks gestation will be analysed against the anaesthetist's difficulty palpating landmarks, the number of insertion attempts and the US measurement of lumbar subcutaneous fat. The aim is to determine if the SCF measurement can be used to predict these outcomes. The observation period will last from the time of the SCF measurement, until the completion of the anaesthetic.
Sponsors
The Royal Brisbane and Women's Hospital
Eligibility
Sex/Gender
All
Age
16 Years to 45 Years
Healthy volunteers
No
Inclusion criteria
All participants must be pregnant (pregnancy is the "health condition" required for eligibility) For part 1: all women presenting to the RBWH for an 18-22 week scan and do not opt-out. For part 2: Women booked for elective caesarean section (Category 4); women who have had a SCF measurement taken at the RBWH on their 18-22 week USS; women who are reasonably expected to have regional anaesthesia for their caesarean section.
Exclusion criteria
Part 1: For the purposes of analysis exclusion criteria will be: referral to the alcohol and drugs service for significant drug or alcohol use; failure to attend at least one antenatal appointment. Part 2: Participants who do not have regional anaesthesia, or have an emergency caesarean section (category 1,2,3).
Outcome results
None listed