None listed
Conditions
Brief summary
The purpose of the study is to show a difference in fatigue measured using physiological outcomes following repeated exercise in three groups of participants. These groups will include, Multiple Sclerosis, Chronic Fatigue Syndrome/Myalgic Encephalopathy and healthy age matched controls. Although individuals with MS, CFS/ME suffer from fatigue, it is expected that the type of fatigue and the way it affects the body is different and therefore the responses to physical incremental exercise separated by 24 hours will be different.
Interventions
Individuals will be asked to visit the Human Performance Lab at Massey University, Palmerston North on two occasions, 24 hours apart. During the first visit, individuals will have height, weight and blood pressure measured. Individuals will then be asked to provide a blood sample from a vein in their arm. Following this individuals will have their radial and corotid artery assessed via pulse wave analysis/velocity. Individuals will complete a 5 minute resting ECG. Each individual will then compl
Individuals will be asked to visit the Human Performance Lab at Massey University, Palmerston North on two occasions, 24 hours apart. During the first visit, individuals will have height, weight and blood pressure measured. Individuals will then be asked to provide a blood sample from a vein in their arm. Following this individuals will have their radial and corotid artery assessed via pulse wave analysis/velocity. Individuals will complete a 5 minute resting ECG. Each individual will then complete an incrememntal cycle ergometer test. Exercise commences at 0W and increased at 15W every minute until exhaustion. On completion of the exercise test you will be asked to repeat the blood sampling and corotid and radial pulse wave analysis/velocity measurement. Finally you will be asked to complete an exercise recovery questionnaire, SF36 questionnaire and the Multidisciplinary fatigue inventory-20. On return to the lab 24 hours later each participant will repeat the radial and corotid pulse wave analysis/velocity assessment, blood sampling, incremental exercise test, exercise recovery questionnaire and Multidisciplinary fatigue inventory. The approximate duration will be an hour and a half for the first day and one hour max on the second data. The tests are administered and supervised by an Exercise Physiologist.
Sponsors
Massey University
Study design
Allocation
Non-randomised trial
Intervention model
Single group
Primary purpose
Diagnosis
Masking
Open (masking not used)
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
Individuals who have been diagnosed with Multiple Sclerosis or ME/Chronic Fatigue Syndrome or that meet the criteria based on the De Paul Symptom Questionnaire and those who are healthy aged matched controls
Exclusion criteria
Individuals with co-mordibities such as cardiovascular disease, diabetes.
Outcome results
None listed