Effect of purple Plum juice on blood pressure in overweight/obese participants.

The effect of Prunus salicina (Queen Garnet) Plum juice on blood pressure in mild hypertensive overweight/obese subjects.

Status

Completed

Phases

Phase 2

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12614001270606

Enrollment

Registered

2014-12-04

Start date

2015-06-16

Completion date

2015-08-31

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Metabolic syndrome is characterised by a cluster of cardiovascular risk factors, including central obesity, elevated blood pressure, dyslipidemia (low HDL cholesterol, high triglyceride levels & LDL cholesterol) and elevated plasma glucose levels. Individuals with metabolic syndrome have central obesity and at least one other risk factor to be clinical diagnosed with the syndrome. Metabolic syndrome is an emerging clinical challenge and imperative public health issue. Subjects with metabolic syndrome have a markedly increased risk of cardiovascular mortality. Prunus salicina, Queen Garnet plum (QGP), is a fruit that was naturally bred to have a high anthocyanin and antioxidant content, in a Queensland Government agriculture initiative. Queen Garnet plums showed anti-obesigenic properties. Studies in laboratory animals have shown that treatment with Queen Garnet plum juice improved the unhealthy blood lipid profile caused by a high-carbohydrate, high-fat diet. The primary object for this study is to monitor blood pressure changes with Queen Garnet plum juice. Blood pressure is measured by using an automatic sphygmomanometer for 12 weeks of duration.

Interventions

Queen garnet plum juice is made from a fresh plums by Department of Agriculture, Fisheries and Forestry, Queensland, Australia. All participants will be requested to drink 200 ml/day juice every morning for a duration of 12 weeks. All participants will be given a juice calendar and were requested to fill in juice calender, every day after drinking juice. Participants were also requested to return the empty juice bottles during their visit to Nutrition clinic every fortnight.

Study design

Allocation

Randomised controlled trial

Intervention model

Parallel

Primary purpose

Treatment

Masking

Blinded (masking used) (Subject, Caregiver, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Healthy volunteers

Inclusion criteria

Participants will need to be overweight with a BMI of greater than 25 or a waist circumference >94cm (male), >80cm (female), systolic blood pressure 130-159 mmHg and diastolic blood pressure 85-99 mmHg.

Exclusion criteria

Liver, kidney and heart disease, pregnancy, type 1 diabetes, type 2 diabetes with any medication, cigarette smoking and the use of any medication for weight loss or hypertension.

Outcome results