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Multicentre prospective study of pulse oximetry to evaluate arterial oxygen saturation in the clinical setting.

In patients requiring an arterial blood gas, a comparison between arterial oxygen saturation and pulse oximetry saturation measurements.

Status
Completed
Phases
Unknown
Study type
Observational
Source
ANZCTR
Registry ID
ACTRN12614001257651
Enrollment
400
Registered
2014-12-02
Start date
2014-12-10
Completion date
2015-11-24
Last updated
2021-06-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Pulse oximetry is commonly used in the clinical setting to titrate oxygen therapy to a target oxygen saturation range in order to avoid the risks of hypoxaemia and hyperoxaemia. The purpose of this study is to investigate the level of agreement between pulse oximeter measured oxygen saturations and arterial blood gas measured oxygen saturations (the gold standard for oxygen saturation measurement) in Australian and New Zealand hospitals.

Interventions

Participants who require an arterial blood gas (ABG) will be identified. At the time of the ABG an oximetry value (SPO2) will be measured, taken from an earlobe or finger probe. The SpO2 value will be the first value measured following visualisation of blood entering the collection vial for the ABG analysis. Only one paired ABG/SpO2 measurement will be recorded for each participant.

Sponsors

Dr Janine Pilcher
Lead SponsorIndividual

Eligibility

Sex/Gender
All
Age
16 Years to No maximum
Healthy volunteers
No

Inclusion criteria

Patients requiring an ABG measurement as part of their clinical care at: Wellington Regional and Christchurch Hospitals in New Zealand; Westmead Prince Charles, Royal North Shore and Concord Hospitals in New South Wales, Australia; Austin Hospital, Victoria, Australia; or Royal Hobart Hospital, Tasmania, Australia.

Exclusion criteria

1. Diagnosis of sickle cell anaemia, methaemoglobinemia, or carbon monoxide (CO) poisoning 2. Patients previously recruited to the study with paired SpO2 and SaO2 values successfully recorded 3. Any other condition which, at the investigator’s discretion, is believed may present a safety risk or impact upon the feasibility of the study or the interpretation of the study results.

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 28, 2026