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The effects of non-invasive brain stimulation on chronic arm pain

The effects of non-invasive brain stimulation on pain and the nociceptive system in people with chronic neuropathic pain

Status
Completed
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12614001247662
Enrollment
30
Registered
2014-11-28
Start date
2014-04-16
Completion date
2016-05-02
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Electrical stimulation of the brain has recently been used as a treatment for people with long-term pain conditions. Currently, it is not certain how brain stimulation is able to reduce pain in these people. The current project proposes to examine changes in the nervous system of people with long-term arm pain who receive a 5-day brain stimulation intervention. The study findings will provide more information on how brain stimulation works and the types of patients who will benefit most from this treatment. This will facilitate the clinical use of brain stimulation for the treatment of long-term pain.

Interventions

Transcranial direct current stimulation. One session per day for 5 days, 20 minutes per session, 1 mA anodal stimulation, delivered by a HDC Kit (Magstim).

Sponsors

Auckland University of Technology
Lead SponsorUniversity

Study design

Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Blinded (masking used) (Subject, Outcomes Assessor)

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years
Healthy volunteers
No

Inclusion criteria

Diagnosis of neuropathic pain in the upper limb by a specialist pain physician, stable chronic pain for at least the preceding 6 months, taking consistent analgesic medication for the preceding 2 months, report a pain score greater than or equal to 3 (0 = no pain and 10 = worst possible pain) during the week preceding the baseline period.

Exclusion criteria

Severe or unstable medical or psychiatric conditions

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026