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Novel Exercise Strategies for the Management of Type 2 Diabetes

In individuals with type 2 diabetes, does high intensity interval exercise training, when compared to continuous moderate aerobic exercise and a control, produce physiological changes in glucose, cardiovascular and fat outcome measures?

Status
Completed
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12614001220651
Acronym
Nil
Enrollment
41
Registered
2014-11-19
Start date
2015-08-03
Completion date
2019-01-20
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Aims and hypotheses: To examine the efficacy of novel versus traditional exercise therapies on metabolic and cardiovascular outcomes in adults with type 2 diabetes. We hypothesize that all exercise interventions will improve abdominal, liver and pancreas fat levels, insulin sensitivity, fitness and cardiovascular health compared with control.

Interventions

Intervention groups: Participants will be randomised into the following groups: a) Supervised high intensity interval training as a single bout of aerobic exercise (4 mins; 90% VO2max) ; b) Supervised traditional prolonged moderate intensity aerobic exercise (45 mins; 60% VO2max); c) control group who will receive standard physical activity and dietary advice. All exercise is to be performed on a stationary cycle ergometer. Exercise sessions are to be completed by the participants 3 times per w

Intervention groups: Participants will be randomised into the following groups: a) Supervised high intensity interval training as a single bout of aerobic exercise (4 mins; 90% VO2max) ; b) Supervised traditional prolonged moderate intensity aerobic exercise (45 mins; 60% VO2max); c) control group who will receive standard physical activity and dietary advice. All exercise is to be performed on a stationary cycle ergometer. Exercise sessions are to be completed by the participants 3 times per week, for a duration of 12 weeks. Participants who are randomised into the high intensity group will progressively increase the duration from 1 minute at 90%VO2max to 4 minutes. The moderate intensity group will incrementally progress in intensity in accordance to training adaptations. All exercising participants will be supervised by an Accredited Exercise Physiologist and records of heart rate and rating of perceived exertion (RPE) will be collected during each exercise session. Blood glucose measures will be taken prior to exercise and if symptoms arise of hypo/hyperglycaemia.

Sponsors

University of Sydney
Lead SponsorUniversity

Study design

Allocation
Randomised controlled trial
Primary purpose
Treatment
Masking
Blinded (masking used)

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years
Healthy volunteers
No

Inclusion criteria

Participants must have type 2 diabetes, body mass index 30-45kg/metres squared, be free from contraindications to exercise training, and not meet the current guidelines for recommended levels of physical activity (3 days a week or > 150 mins per week)

Exclusion criteria

Health contraindications to exercise.

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 23, 2026