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Does resistance exercise training improve muscle strength and function in acute burn injury?

A randomised, controlled trial investigating the effect of resistance training on muscle strength, function and quality of life in acute burn injury.

Status
Completed
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12614001156673
Enrollment
48
Registered
2014-10-31
Start date
2014-11-08
Completion date
2017-11-12
Last updated
2020-03-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

It is known that survivors of burn injury often experience impairments in strength and functional ability for the rest of their life. This is a result of losses in skeletal muscle mass and strength. This study aims to investigate the effect of resistance training on the muscle mass, strength and quality of life of a burns patient. It is expected that patients who undertake a structured resistance exercise training program will exhibit increased muscle mass, increased strength and an improved quality of life compared to the control group.

Interventions

Both intervention (EIG) and control (CG) groups will receive standard Physiotherapy input which typically consists of bi-daily intervention. The EIG will undergo a prescribed resistance exercise program in their afternoon Physiotherapy session which will last for approximately 60 mins, three times per week. The resistance training program will be Physiotherapy-led and will comprise 3 sets of 10 repetitions of exercises for shoulders, biceps, triceps, quadriceps and lower limb complex at a loa

Both intervention (EIG) and control (CG) groups will receive standard Physiotherapy input which typically consists of bi-daily intervention. The EIG will undergo a prescribed resistance exercise program in their afternoon Physiotherapy session which will last for approximately 60 mins, three times per week. The resistance training program will be Physiotherapy-led and will comprise 3 sets of 10 repetitions of exercises for shoulders, biceps, triceps, quadriceps and lower limb complex at a load of 70% of 1 repetition max, as determined by pre-session strength assessments. The intervention period will continue for 4 weeks. There will be a break from intervention of at least 3 days following skin grafting procedures to allow for adequate wound healing. Assuming each patient will undergo one surgical procedure, we will aim for a minimum 10 exercise sessions for each patient during the intervention period. This may require addiditonal sesisons beyond the 4 week period to achieve 10 sessions.

Sponsors

Paul Gittings
Lead SponsorIndividual

Study design

Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Blinded (masking used) (Subject, Outcomes Assessor)

Eligibility

Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

Adults (above 18 years of age) admitted to the Western Australian State Adult Burns Unit with an acute burn injury. TBSA 5-40%. Able to give consent within 72 hours of admission.

Exclusion criteria

Discharge within 72 hours. Burns to palmar hands. Electrical injury. Multi trauma or injury severe enough to warrant amputation. Pre-existing musculoskeletal injuries excluding patients from exercising. Type 1 diabetes or other metabolic conditions. Neurological conditions or poor English language (requiring interpreter). Unable to cooperate with the exercise program

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026