None listed
Conditions
Brief summary
Aspiration pneumonia or pneumonitis is a fatal complication under general anaesthesia. Current fasting guidelines before general anaetshesia recommend 2 hours for clear fluid and 6 hours for light meal. However the guidelines do not account for the fact that some fasted surgical patients may still not have empty stomachs at that time of their surgery. The technique of gastric ultrasound to determine the types of gastric contents and the volume has been well described and standardised. The hypothesis of this study is gastric volume will return to baseline more rapidly after ingestion of clear fluid as compared to a fluid equivalent of a standard meal.
Interventions
Twenty volunteers will fast at least for 6 hours for food and for 2 hours for clear liquid prior to this study. Gastric ultrasound is done to determine the baseline gastric residual volume (GRV). The volunteers are then randomised into two groups, one receiving 250mls of nutritional liquid (Up and Go, which contains protein 8.3g, total fat 3.8g, saturated fat 0.5g, carbohydorate 30.3g, sugars 19.0g, sodium 163mg, dietary fibre 3.8g, monounsaturated 1.5g, polyunsaturated 1.8g, potassium 538mg, fo
Twenty volunteers will fast at least for 6 hours for food and for 2 hours for clear liquid prior to this study. Gastric ultrasound is done to determine the baseline gastric residual volume (GRV). The volunteers are then randomised into two groups, one receiving 250mls of nutritional liquid (Up and Go, which contains protein 8.3g, total fat 3.8g, saturated fat 0.5g, carbohydorate 30.3g, sugars 19.0g, sodium 163mg, dietary fibre 3.8g, monounsaturated 1.5g, polyunsaturated 1.8g, potassium 538mg, folic acid 100mcg, viatminA 128mcg, Vitamin B1 0.28mg, Vitamin B2 0.28mg, Vitamin B3 2.5mg, Vitamin B6 0.40mg, Vitamin B12, Vitamin C 10.0mg, calcium 400mg, energy 198cal) and the other 250mls of clear fluid (water). Gastric ultrasound is done immediately post ingestion then every 10 minutes for the 1st 30 mins then every hour until the gastric volume returns to baseline. After each volunteer's gastric volume has returned to baseline, he/she will then crossover to the other group and the process is repeated.
Sponsors
Department of Anaesthesia and Pain Medicine at Royal Perth Hospital
Study design
Allocation
Randomised controlled trial
Intervention model
Crossover
Primary purpose
Prevention
Masking
Open (masking not used)
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
Healthy volunteers
Exclusion criteria
Previous gastro-oesophageal surgery or abnormality of the gastrointestinal tract Recent Pregnancy (within 3 months) Age less than 18 Unable to give informed consent themselves Hiatus Hernia History of gastroesophageal reflux Cognitive impairement/ mental disability Those unable to lie still
Outcome results
None listed