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The safe administration of large volume of intravenous fluids in colonoscopy patients to prevent hypotension- guided by patients' level of fluid tolerance on inferior vena cava ultrasound.

The safe administration of large volume of intravenous fluids in colonoscopy patients to prevent hypotension- guided by patients' level of fluid tolerance on inferior vena cava ultrasound.

Status
Completed
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12614001071617
Enrollment
128
Registered
2014-10-07
Start date
2014-11-05
Completion date
2015-01-16
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Colonoscopy patients are often "dry" or dehydrated as a result of the bowel preparation. This often results in a drop in blood pressure during the procedure. A study in 2006 showed that by giving patients 15ml/kg of fluid, it did not result in improvement of blood pressures, and it was postulated that the volume infused could have been insufficient. In our study, we plan to give 30ml/kg of fluid to colonoscopy patients before their procedure, as we hypothesise that 30ml/kg may be enough to prevent or reduce the drop in blood pressures. We aim to do this by using echocardiography (taking a picture of the heart) to titrate fluids so that patients will not be overloaded with fluids.

Interventions

Hartmann's solution 30ml/kg intravenously pre-operatively, titrated according to level of fluid tolerance on echocardiography.

Sponsors

Dr. Peter Reid
Lead SponsorIndividual

Study design

Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Blinded (masking used) (Subject, Outcomes Assessor)

Eligibility

Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

All patients presenting for elective colonoscopy.

Exclusion criteria

1. Patient refusal to participate. 2. Language barrier. 3. Medical contraindications (e.g. severe uncontrolled congestive cardiac failure/renal failure) 4. Time constraints (e.g. administrative pressure to get the elective colonoscopy list finished on time).

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026