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Influence of sympathetic nerve activity on pain propagation in sciatica patients

For trigger points (TrPs) positive sciatica patients compared to TrPs-negative sciatica subjects, will dry needling provoke vasomotor reactions in the pain area, and thus confirm the influence of the sympathetic nerve activity in pain propagation of sciatica subjects?

Status
Completed
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12614001060639
Enrollment
50
Registered
2014-10-03
Start date
2013-07-14
Completion date
2014-09-12
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Short-term vasodilation after dry needling under IRT control of active TrPs was recorded in several cases and it is unknown whether noxious stimulation of every active trigger point can provoke vasomotor reactions. Moreover, the presence of trigger points in sciatica patients secondary to a primary lesion, e.g. a vertebral disc lesion, was suggested, but it is unknown how often they occur. The aim of this study is to evaluate the prevalence of active trigger points among subacute sciatica patients and response to dry needling under IRT control of TrPs positive and negative subacute sciatica patients.

Interventions

All of the sciatica subjects will be diagnosed by an experienced specialist for myofascial pain syndrome co-existence – gluteus minimus active trigger points presence based on Travell and Simons’ diagnostic criteria. Active trigger points (TrPs) were confirmed if spot tenderness, recognition of pain and digitally evoked referred pain pattern of the gluteus minimus were present. The localization of the most active trigger points or two most tender points (non-TrPs subjects) will be mark. After my

All of the sciatica subjects will be diagnosed by an experienced specialist for myofascial pain syndrome co-existence – gluteus minimus active trigger points presence based on Travell and Simons’ diagnostic criteria. Active trigger points (TrPs) were confirmed if spot tenderness, recognition of pain and digitally evoked referred pain pattern of the gluteus minimus were present. The localization of the most active trigger points or two most tender points (non-TrPs subjects) will be mark. After myofascial pain evaluation, all patients will be asked to define their pain level on the visual analogue scale and to draw their current pain pattern on a diagram. Then, infrared thermovision (IRT) camera side-to-side comparison of the painful area and the opposite extremity will be performed in the standing position. On the same day, patients will receive a dry needling session under infrared thermovision camera control regarding TrPs presence. The time of needling will be 5 minutes for every given point. During the whole procedure, the subarea of referred pain reported by the patient will be recorded. After the needling of the both marked points, further (6 consecutive minutes) thermovision imaging will be performed

Sponsors

National Science Centre
Lead SponsorGovernment body

Study design

Allocation
Non-randomised trial
Intervention model
Parallel
Primary purpose
Diagnosis
Masking
Blinded (masking used) (Subject, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender
All
Age
30 Years to 60 Years
Healthy volunteers
No

Inclusion criteria

diagnosis of sciatica, age between 30 and 60 (inclusive); both lower limbs present, pain duration 1-3 months, >3 on the 1-10 point VAS scale of leg pain, with this being the dominant pain problem

Exclusion criteria

complex regional pain syndrome, cauda equina syndrome, previous back surgery, spinal tumors, scoliosis, pregnancy, coagulant treatment, disseminated intravascular coagulation, diabetes, epilepsy, infection, inflammatory rheumatologic diseases, stroke, or oncological history.

Outcome results

None listed

Source: ANZCTR · Data processed: Mar 17, 2026