How androgens exert their anabolic effects: effects of oral testosterone on protein metabolism in healthy men.

How androgens exert their anabolic effects. Effects of oral testosterone on protein metabolism in healthy men.

Status

Not yet recruiting

Phases

Phase 4

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12614001045606

Acronym

Oral testosterone study

Enrollment

Registered

2014-09-29

Start date

2014-10-01

Completion date

Unknown

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Observations from previous studies suggest that testosterone acts on liver to induce protein anabolic effect. We will test the hypothesis that testosterone by acting on the liver, preserves protein loss in healthy men.

Interventions

Oral micronised testosterone 40 mg daily for 14 days. Adherence to treatment will be monitored by drug return.

Study design

Allocation

Non-randomised trial

Intervention model

Single group

Primary purpose

Treatment

Masking

Open (masking not used)

Eligibility

Sex/Gender

Male

Age

60 Years to 75 Years

Healthy volunteers

Yes

Inclusion criteria

Healthy men

Exclusion criteria

Endocrine disorders

Outcome results