Skip to content

The effect of a short term, supervised exercise training intervention on longitudinal left ventricular function in patient with heart failure with preserved ejection fraction

In patients with Heart Failure with Preserved Ejection Fraction (HFPEF), does short term supervised exercise training improve left ventricular longitudinal intrinsic function (global longitudinal strain)?

Status
Not yet recruiting
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12614001042639
Acronym
SET-HFPEF
Enrollment
25
Registered
2014-09-26
Start date
2014-10-07
Completion date
Unknown
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

The aim of this study is to determine whether short term supervised exercise training improves the LV longitudinal intrinsic function in HFPEF patients. hypothesis: short term supervised exercise training improves LV longitudinal intrinsic function in HFPEF patient

Interventions

One on one training with physiotherapist or sport trainer or registered nurse. The exercise training will be 1 hour per day, 5 times a week for one month. Intermittent and interval walking with upgrading to treadmill after two weeks exercise. Intermittent and interval waking protocol is 3 mins x fast paced walking at 70-80% max HR then followed by 2 mins slow recovery walking and repeated for 1 hour. The exercise walking will be done in division of preventive rehabilitation facility building f

One on one training with physiotherapist or sport trainer or registered nurse. The exercise training will be 1 hour per day, 5 times a week for one month. Intermittent and interval walking with upgrading to treadmill after two weeks exercise. Intermittent and interval waking protocol is 3 mins x fast paced walking at 70-80% max HR then followed by 2 mins slow recovery walking and repeated for 1 hour. The exercise walking will be done in division of preventive rehabilitation facility building for 2 weeks duration and changed to treadmill for remaining 2 weeks. The intensity of exercise is based on 70-80% maximal heart rate and 65% VO2max. Each patient will be followed up on call and survey to their house.

Sponsors

Sidhi Laksono Purwowiyoto
Lead SponsorIndividual

Study design

Allocation
Non-randomised trial
Intervention model
Single group
Primary purpose
Treatment
Masking
Open (masking not used)

Eligibility

Sex/Gender
All
Age
55 Years to 65 Years
Healthy volunteers
No

Inclusion criteria

symptomatic HF NYHA class II-III, good LV EF (> 50%), diastolic dysfunction (more than grade I), NT pro BNP > 220pg/ml, BNP > 200 pg/ml, global normokinetic (no regional wall motion abnormality)

Exclusion criteria

valvular heart disease (more than moderate), pulmonary disease (COPD, moderate to severe asthma), acute coronary syndrome, stable angina pectoris, relevant musculoskeletal disease, symptomatic arrhytmias, BP > 150/100 mmHg

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 22, 2026