None listed
Conditions
Brief summary
The aim of this study is to determine whether short term supervised exercise training improves the LV longitudinal intrinsic function in HFPEF patients. hypothesis: short term supervised exercise training improves LV longitudinal intrinsic function in HFPEF patient
Interventions
One on one training with physiotherapist or sport trainer or registered nurse. The exercise training will be 1 hour per day, 5 times a week for one month. Intermittent and interval walking with upgrading to treadmill after two weeks exercise. Intermittent and interval waking protocol is 3 mins x fast paced walking at 70-80% max HR then followed by 2 mins slow recovery walking and repeated for 1 hour. The exercise walking will be done in division of preventive rehabilitation facility building for 2 weeks duration and changed to treadmill for remaining 2 weeks. The intensity of exercise is based on 70-80% maximal heart rate and 65% VO2max. Each patient will be followed up on call and survey to their house.
Sponsors
Study design
Eligibility
Inclusion criteria
symptomatic HF NYHA class II-III, good LV EF (> 50%), diastolic dysfunction (more than grade I), NT pro BNP > 220pg/ml, BNP > 200 pg/ml, global normokinetic (no regional wall motion abnormality)
Exclusion criteria
valvular heart disease (more than moderate), pulmonary disease (COPD, moderate to severe asthma), acute coronary syndrome, stable angina pectoris, relevant musculoskeletal disease, symptomatic arrhytmias, BP > 150/100 mmHg