A randomized trial of preoperative oral carbohydrates in abdominal surgery

Patients undergoing different abdominal operations taking preoperative oral intake of carbohydrates show different postoperative well-being (VAS) scores

Status

Completed

Phases

Unknown

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12614000995673

Enrollment

150

Registered

2014-09-16

Start date

2010-01-03

Completion date

2012-12-28

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

This study purposes to provide conclusive clinical evidence as to whether or not the preoperative administration of oral carbohydrate-rich solutions is effective on patient outcome, testing the hypothesis on patients undergoing colorectal surgery or cholecytectomy surgery.

Interventions

For the study group, the beverage contained 12.5% carbohydrates (poly-carbohydrates), 50 kcal/100 mL, 285 mOsmol/kg (NutriciapreOp, Nutricia Ltd.) The study group received 800 mL (administered orally) of carbohydrate beverage in the evening before surgery (22:00) and an additional 400 mL 2 h before anesthesia induction.

Study design

Allocation

Randomised controlled trial

Intervention model

Parallel

Primary purpose

Treatment

Masking

Blinded (masking used) (Subject, Caregiver, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Healthy volunteers

Inclusion criteria

Inclusion criteria were patients undergoing an operation of the colon and rectum for benign and malignant diseases, or open abdominal cholecystectomy for chronic cholecystitis.

Exclusion criteria

Type 1 or 2 diabetes mellitus, stomach emptying disorders or documented gastric esophageal reflex disease, emergency surgery interventions, or refusal of the patient to participate in the trial.

Outcome results