Skip to content

High speed photography to determine the presence or absence of airborne droplets in the exhaled air of subjects wearing high flow nasal cannulae (OptiflowTM) with calculations of trajectory and drying time

Airborne droplet generation in the exhaled air of healthy subjects wearing high flow nasal cannulae

Status
Completed
Phases
Unknown
Study type
Observational
Source
ANZCTR
Registry ID
ACTRN12614000924651
Enrollment
6
Registered
2014-08-28
Start date
2010-01-08
Completion date
2013-11-30
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Humidified High Flow Nasal cannulae (Optiflow Trademark Fisher and Paykel Healthcare, Auckland, New Zealand) are in use in many clinical settings including the home and the hospital. These cannulae are used to deliver a range of flows of heated and humidified gases to support patients with a variety of conditions including those with a compromised respiratory status. It is thought that whilst patients are on this therapy that their exhaled gases laden with viral airborne droplets (aerosols) may lead to an increased infection control risk. Determining both the potential dispersal of viruses via aerosol and whether the use of a cannula generates more exhaled droplets compared to normal resting breathing and forced nasal exhalation (snorting), is vital as this shall help inform any control measures. The hypothesis under consideration was that Optiflow use does not pose an increased risk of Hospital Acquired Infections (HAI’s) from an infection prevention and control perspective.

Interventions

Humidified high flow nasal cannulae are used in many clinical settings including the home and acute care hospital settings such as high dependency units and intensive care units. These cannulae are used to deliver a range of flows up to 60L/min of heated and humidified gases to support patients with compromised respiratory function. It is thought that airborne droplets in the exhaled gases may lead to the spread of respiratory viruses. Defining the potential dispersal of viruses via aerosol is

Humidified high flow nasal cannulae are used in many clinical settings including the home and acute care hospital settings such as high dependency units and intensive care units. These cannulae are used to deliver a range of flows up to 60L/min of heated and humidified gases to support patients with compromised respiratory function. It is thought that airborne droplets in the exhaled gases may lead to the spread of respiratory viruses. Defining the potential dispersal of viruses via aerosol is essential for the development of prevention measures therefore to determine if the cannula generates more exhaled droplets than compared to natural breathing is vital High speed photography shall be used to determine the presence or absence of airborne droplets when high flow nasal cannulae are used in six participants at 30 and 60L/min respectively. Duration 5-10 mins.

Sponsors

University of Canterbury
Lead SponsorUniversity

Eligibility

Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

Healthy volunteers who have consented to participate

Exclusion criteria

Unable or willing to give consent

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 16, 2026