None listed
Conditions
Brief summary
The Cooperative National Registry of Acute Coronary care, Guideline Adherence and Clinical Events (CONCORDANCE) is an Australian observational registry that describes management and outcomes in patients with Acute Coronary Syndromes (ACS) and feeds back both performance and outcome measures to participating hospitals.
Interventions
The Cooperative National Registry of Acute Coronary care, Guideline Adherence and Clinical Events (CONCORDANCE) is an Australian observational registry that describes the management and outcomes of patients with Acute Coronary Syndromes (ACS). Performance measures and patient outcomes are returned in real-time to participating hospitals benchmarked against the study aggregate for the purpose of reporting variation in care in-hospital. Patients are then followed for 12 months for readmission to h
The Cooperative National Registry of Acute Coronary care, Guideline Adherence and Clinical Events (CONCORDANCE) is an Australian observational registry that describes the management and outcomes of patients with Acute Coronary Syndromes (ACS). Performance measures and patient outcomes are returned in real-time to participating hospitals benchmarked against the study aggregate for the purpose of reporting variation in care in-hospital. Patients are then followed for 12 months for readmission to hospital for cardiovascular disease, medication compliance and access to secondary prevention.
Sponsors
Sydney Local Health District
Eligibility
Sex/Gender
All
Age
18 Years to 120 Years
Healthy volunteers
No
Inclusion criteria
All patients must have symptoms of an ACS plus one of the following: ECG changes, elevated enzymes, previous history of CAD, new documentation of CAD or two features of high risk ACS. Patients are eligible if they present to hospital with symptoms felt to be consistent with acute cardiac ischaemia for >10mins within 24 hours of presentation to hospital plus one of the following: ECG changes; elevated enzymes; documentation of CAD or documentation of 2 or more high risk features for CAD. ECG changes: - transient ST segment elevation of 0.5mm in two or more contiguous leads; - ST segment depression of 0.5mm in two or more contiguous leads - new T wave inversion of 1 mm in two or more contiguous leads - new Q waves (1/3 height of R wave or >0.04 seconds) - new R wave > S wave in lead V1 (posterior MI) - new left bundle branch block Increase in cardiac enzymes: - increase in troponin T above the upper limit of normal; - increase in troponin I above the upper limit of normal; - CK-MB 2x upper limit of the hospitals normal range or if there is no CK-MB available, then total CK greater than the upper limit of normal. Documentation of Coronary Artery Disease: - history of MI, angina, congestive cardiac failure due to ischaemia or resuscitated sudden cardiac death; - history of, or new positive stress test with or without imaging; - prior or new, cardiac catheterisation documenting coronary artery disease; - prior, or new percutaneous coronary artery intervention or coronary artery bypass graft surgery. At least 2 of the following High Risk features: - haemodynamic compromise (BP<90 and HR >100) - left ventricular systolic dysfunction (LVEF<0.40); - presence of known diabetes - documentation of chronic kidney disease (estimated GFR <60mls/min
Exclusion criteria
The qualifying acute coronary syndrome must not be precipitated or accompanied by a co-morbidity such as trauma or major bleeding and patients already hospitalised for any reason when the ACS develops are not eligible for enrolment in CONCORDANCE.
Outcome results
None listed