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Treatment of Childhood Trauma: What Works Best in Reducing Trauma Symptoms for People Who Experienced a Traumatic Event in Childhood

International multi-centre RCT comparing the effectiveness of Imagery Rescripting and Eye Movement Desensitisation and Reprocessing as treatment for adults with Post-Traumatic Stress Disorder (PTSD) related to childhood trauma in reducing severity of PTSD symptoms and improving quality of life

Status
Completed
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12614000750684
Acronym
IREM
Enrollment
155
Registered
2014-07-16
Start date
2014-10-08
Completion date
2018-06-18
Last updated
2020-02-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Comparing two treatment approaches, Imagery Rescripting (ImRs) and Eye Movement Desensitisation and Reprocessing (EMDR), for adults with PTSD related to childhood based trauma. ImRs is where the individual imagines a different ending to the trauma memory, so that the person can change the meaning of the event. EMDR uses a sequence of eye movements to help an individual to reprocess thoughts and feelings associated with trauma experiences. This purpose of this research is to compare the effectiveness of these two approaches and to test if the element of the treatments that facilitate change is the same for both approaches.

Interventions

Comparing the effectiveness of Imagery Rescripting (ImRs) and Eye Movement Desensitization and Reprocessing (EMDR) as treatment of childhood-trauma related PTSD in adults ImRs: ImRs is a technique where an individual imagines a different course of the trauma events that helps to satisfy the needs of the person. This in turn leads to a change in the meaning of the events. ImRs is considered especially suited for events of an interpersonal nature where an individuals trust of others was violated,

Comparing the effectiveness of Imagery Rescripting (ImRs) and Eye Movement Desensitization and Reprocessing (EMDR) as treatment of childhood-trauma related PTSD in adults ImRs: ImRs is a technique where an individual imagines a different course of the trauma events that helps to satisfy the needs of the person. This in turn leads to a change in the meaning of the events. ImRs is considered especially suited for events of an interpersonal nature where an individuals trust of others was violated, where there is an inappropriate degree of level responsibility for the event, and where core needs of dependency and safety were threatened. EMDR: A psychotherapeutic treatment approach which uses a sequence of eye movements to facilitate emotional-cognitive processing of disturbing experiences. EMDR asks individuals to recall their trauma experience into their minds while at the same time tracking the back and forth movements of the therapist's finger. The effect of this treatment process is it helps to alleviate lingering effects of the trauma, allowing the individual to reprocess the traumatic experience, and to develop more adaptive coping skills. The research will follow the treatment protocol for each of these treatments. Random allocation using random number tables controlled by central researcher in Holland. Participants will receive a maximum of 12, 90 minute sessions twice a week in either ImRs or EMDR. Individual treatment sessions will be with a registered psychologist or psychiatrist.

Sponsors

University of Western Australia
Lead SponsorUniversity

Study design

Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Blinded (masking used) (Outcomes Assessor)

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years
Healthy volunteers
No

Inclusion criteria

DSM-IV diagnosis of PTSD, as assessed with the SCID-II or MINI PTSD as main complaint PTSD diagnosis lasting for 3 months or more Trauma that occurred prior to the age of 16 years old and participant agrees that this is the main focus of treatment If recent trauma - happened more than 6 months ago Aged between 18 and 70 years old Able to understand, read, and write country of participation language (Dutch, German or English)

Exclusion criteria

Acute PTSD DSM-IV diagnosed alcohol or drug dependence Benzodiazepine use (participant can participate if they stop benzodiazepine and they have been abstinent for at least 2 weeks) Comorbid psychotic disorder DSM-IV Bipolar disorder, type 1 Acute suicide risk IQ of 80 or less Scheduled to begin another form of PTSD treatment PTSD focused treatment within the past 3 months Participants should not start/continue any form of psychological therapy or medication during the screening, treatment, and waitlist stage (up to 8 weeks post-treatment assessment) Changes in medication within last 3 months Not able to plan 12 x 90 minutes treatment sessions twice a week within 6-8 weeks

Outcome results

None listed

Source: ANZCTR · Data processed: Mar 10, 2026