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Studying the effect of adenomyosis on the subendometrial blood flow and Junctional zone measurement in comparison to normal subjects.

comparative study of the subendometrial vascular indices and junctional zone measurement in women with adenomyosis and women without using ultrasound 3D power Doppler

Status
Not yet recruiting
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12614000693628
Enrollment
120
Registered
2014-07-02
Start date
2014-07-05
Completion date
2014-12-26
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

we studied the Endometrial vascular indices and junctional zone measurement in women who were diagnosed of having either fibroids or adenomyosis by ultrasound and who had hysterectomy in comparison for age-matched women who have a free ultrasound examination.

Interventions

trans-vaginal 3D power Doppler Ultrasonographic examination was done by Voluson 730 Registered trademark , Expert ultrasound system (GE Healthcare, Zipf, Austria) with transvaginal 5-to 9-MHz volume transducer,).The ultrasound examination was preformed prior to hysterectomy. The ultrasonographic examination provided data related to vascular index (VI), flow index (FI), and vascular-flow index (VFI). The region of interest included the entire region of the endometrium.After evaluating the total

trans-vaginal 3D power Doppler Ultrasonographic examination was done by Voluson 730 Registered trademark , Expert ultrasound system (GE Healthcare, Zipf, Austria) with transvaginal 5-to 9-MHz volume transducer,).The ultrasound examination was preformed prior to hysterectomy. The ultrasonographic examination provided data related to vascular index (VI), flow index (FI), and vascular-flow index (VFI). The region of interest included the entire region of the endometrium.After evaluating the total color percentage and flow amplitude for the volume of interest, The virtual organ computer aided analysis (VOCAL) software for the analysis of 3D power Doppler histograms was used with computer algorithms to form indices of blood flow and vascularization. In the 730 system, there are four rotation angles to choose from, namely, 6 degrees, 9 degrees , 15 degrees , and 30 degrees, and because the entire data set is rotated about 180 degrees, these result in 30, 20, 12, and 6 planes, respectively, being available for measurements.We used rotation angle 30 degrees in this study .That means rotation in 6 planes manually.The approxiamate time of the test from 15-20 minutes.

Sponsors

Eman Elkattan
Lead SponsorIndividual

Study design

Allocation
Non-randomised trial
Intervention model
Single group
Primary purpose
Diagnosis
Masking
Blinded (masking used) (Investigator, Outcomes Assessor)

Eligibility

Sex/Gender
All
Age
35 Years to 60 Years
Healthy volunteers
No

Inclusion criteria

-women with ultrasound diagnosis of adenomyosis only and scheduled for hysterectomy confirmed by histopathology -women with ultrasound that confirms normal pelvic study and are asymptomatic and age matched

Exclusion criteria

-women with combined adenomyosis and fibroids -women with fibroid or adenomyosis and are not scheduled for hysterectomy -women with fibroids

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026