None listed
Conditions
Brief summary
Epidemiological studies have consistently demonstrated that fruit consumption is inversely associated with the risk of diabetes. The form and type of fruit consumed may affect glycaemic response, which could influence advocacy for pre-diabetics and diabetics. The objective of the present study is to compare the effects of different forms (puree, bites) of guava and papaya on postprandial glucose concentrations, dietary compensation, and satiety among young adults and elderly. It is hypothesized that the consumption of small particle size fruits (e.g. puree) with short oral residence time and high eating rate is likely to cause greater spikes in glycaemic response than fruits with larger particle size (e.g. bites). On the other hand, fruits with large particle size that require more chewing and slow eating rate may blunt postprandial glycaemic response, promote satiety and result in greater dietary compensation and lower energy intake than fruits with small particle size. In addition, it has been hypothesized that young adults and elderly may have different glycaemic and satiety responses to the consumption of different forms (puree, bites) and types of fruits (guava and papaya) due to the differences in their oral processing ability.
Interventions
This will be a randomised crossover study with four arms each containing 25 g of carbohydrate:
Arm 1: Guava puree
Arm 2: Guava bites
Arm 3: Papaya puree
Arm 4: Papaya bites
The results of these four treatments will be compared with the glucose beverage (reference). Guava and papaya have been chosen as they are popular tropical fruits in South East Asia and they differ in their sensory properties, i.e. colour, smell, taste, and texture.
All potential participants will be asked to provide infor
This will be a randomised crossover study with four arms each containing 25 g of carbohydrate: Arm 1: Guava puree Arm 2: Guava bites Arm 3: Papaya puree Arm 4: Papaya bites The results of these four treatments will be compared with the glucose beverage (reference). Guava and papaya have been chosen as they are popular tropical fruits in South East Asia and they differ in their sensory properties, i.e. colour, smell, taste, and texture. All potential participants will be asked to provide informed consent during their screening session. They will then be asked to complete a screening questionnaire to determine their eligibility. Once their eligibility is confirmed, baseline measurements including anthropometric measurements, blood pressure, diet record, and physical activity level, will be collected from each participant. Following this, participants will be asked to attend a testing session on seven occasions: glucose beverage (reference) on three occasions, guava puree, guava bites, papaya puree, and papaya bites on a single occasion, where glycaemic index, dietary compensation, and satiety of each treatment will be measured. There will be at least a-day washout between treatments.
Sponsors
Singapore Institute for Clinical Sciences, A*STAR
Study design
Allocation
Randomised controlled trial
Intervention model
Crossover
Primary purpose
Prevention
Masking
Blinded (masking used) (Investigator)
Eligibility
Sex/Gender
All
Age
21 Years to 75 Years
Healthy volunteers
Yes
Inclusion criteria
The inclusion criteria are healthy males and females between the ages of 21 and 35 years or between the ages of 61 and 75 years.
Exclusion criteria
The exclusion criteria are - People with major chronic disease such as heart disease, cancer or diabetes mellitus - People with family history of diabetes - Individuals with food intolerances or allergies to test products - Individuals who are taking insulin or drugs known to affect glucose metabolism and body fat distribution - People with a major medical or surgical event requiring hospitalization within the preceding 3 months - Individuals with the presence of disease or drugs which influence digestion and absorption of nutrients - Pregnant women
Outcome results
None listed