None listed
Conditions
Brief summary
To investigate the effects of sugammadex and neostigmine on IOP, hemodynamic parameters, and complications after extubation. Patients aged 18–65 years with a risk status of ASA I–II who underwent arthroscopic surgery under general anesthesia. The patients were randomly assigned into 2 groups. At the end of the surgery, the neuromuscular block was reversed using neostigmine (40–50 microg/kg) and atropine (15 microg/kg) in group 1, and sugammadex (4 mg/kg) in group 2. IOP were measured before induction and at 30 sec and 2 and 10 min after extubation. A Tono-Pen XL applanation tonometer (Medtronic Solan, Jacksonville, FL, USA) was used to measure IOP.
Interventions
Sugammadex is the intervention of the study. This drug is the first selective relaxant binding agent. In the study, sugammadex was given as an intravenous injection and each patient received only a single dose . The dosage of Sugammadex is 4mg/kg. Sugammadex was administered at the completion of surgery.
Sponsors
Sedat Hakimoglu
Study design
Allocation
Randomised controlled trial
Primary purpose
Treatment
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
Patients aged 18–65 years with ASA I–II risk status who underwent arthroscopic surgery under general anesthesia
Exclusion criteria
Patients with chronic diseases other than hypertension, those who had previously undergone ocular surgery, and those with previous ocular diseases were excluded. In addition, patients allergic to tetracaine or other agents used in anesthesia were excluded
Outcome results
None listed